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Immunology PhD Projects

We have 116 Immunology PhD Projects

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Showing 1 to 30 of 116
  Immune Responses to Salivary Biomarkers as Tools to Understand the Epidemiology of Vector Borne Diseases
  Dr J Sternberg, Dr A Bowman
Applications accepted all year round

Funding Type

PhD Type

Haematophagous (blood-feeding) arthropods may act as vectors for serious parasitic diseases to humans and livestock. Examples include ticks (Lyme diseases, tick-borne encephalitis, theileriosis), Hemipteran Bugs (Chagas disease), Tsetse Flies (African trypanosomiasis), Mosquitoes (malaria, filariasis, dengue etc).
  Novel microbes and their biochemistry in C. elegans
  Prof S Mani
Applications accepted all year round

Funding Type

PhD Type

The Mani Laboratory @The Albert Einstein College of Medicine, INC has an open position for a highly motivated postdoctoral fellow to be part of an expanding research program on novel aspects of the microbial biofilms and C.
  Disrupting the regulatory mechanisms that allow hospital acquired infections to resist antibiotic therapy.
  Dr R McCarthy
Applications accepted all year round

Funding Type

PhD Type

The discovery of penicillin over 90 years ago and its subsequent uptake by healthcare systems around the world revolutionised global health and wellbeing.
  Egr2 and 3 mediated T cell tolerance in cancer and their impact in immune checkpoint therapy
  Dr S Li
Applications accepted all year round

Funding Type

PhD Type

Tumour infiltrated lymphocytes (TILs) contain tumour reactive T cells and have been used as adoptive cell transfer therapy in patients which can mediate cancer regression.
  Telomere length elongation following treatment with chemotherapeutic drugs. Aim: To investigate the mechanisms which leads to telomere length elongation after treatment with tricostatin A and azacytidine.
  Dr T Roberts
Applications accepted all year round

Funding Type

PhD Type

Telomeres are specialised structures, which are present at the ends of chromosomes and serve to protect the chromosome from degradation during cell division.
  PhD in Child Health - Volatile Organic Compounds (VOC) for diagnosis in ex-preterm children
  Dr W Watkins, Dr M Chakraborty, Prof S Kotecha
Applications accepted all year round

Funding Type

PhD Type

This is a self-funded/sponsored PhD opportunity. BACKGROUND. Bronchopulmonary dysplasia (BPD) is a major respiratory consequence of premature birth (Walsh et al., 2006).
  The phenotypic and functional identification of angiogenic T-cells for potential use to treat cardiovascular disease Project ID SAS0043
  Dr M Ross, Dr G Wright
Application Deadline: 31 May 2020

Funding Type

PhD Type

PROJECT DESCRIPTION. This project is based within the School of Applied Sciences at Edinburgh Napier University and is led by Dr.
  Investigating the role of connexins in the gingival response to the oral microbiota
  Dr J Butcher, Dr C Wright, Dr P Martin
Applications accepted all year round

Funding Type

PhD Type

Project reference number. SHLS19005. Periodontal disease (PD) is a chronic inflammatory and bone destructive disease that imposes a substantial social and economic burden, and has been linked to the initiation and progression of cardiovascular disease, diabetes, rheumatoid arthritis, and Alzheimer’s disease.
  Bioengineering of innovative functional biomaterials for diagnosis of Q fever
  Prof Bernd Rehm
Applications accepted all year round

Funding Type

PhD Type

Q fever is an infection by the intracellular pathogen Coxiella burnetii that can cause a severe flu-like illness. The sensitive and specific diagnosis of Q fever is important for early intervention and for control and management of the disease.
  Development of nature-inspired polyester particles for cancer vaccines
  Prof Bernd Rehm
Applications accepted all year round

Funding Type

PhD Type

Advances in synthetic biology allows recombinant bacteria to produce protein coated polyester particles. These polyester particles have been utilized as particulate vaccines against bacterial and viral infections.
  Self-assembled particulate vaccines for prevention of Q fever
  Prof Bernd Rehm
Applications accepted all year round

Funding Type

PhD Type

Q fever is an infection by the intracellular pathogen Coxiella burnetii that can cause a severe flu-like illness. For some people, Q fever can affect their health and ability to work for many years.
  Synthetic biology toward innovative virus-like particles
  Prof Bernd Rehm
Applications accepted all year round

Funding Type

PhD Type

Virus-like particles (VLP) are self-assembled viral proteins that do not contain genetic material and are non-infectious. VLPs have been successfully developed into particulate vaccines for prevention of viral infections such as human papilloma virus or Hepatitis B.
  Understanding resistance and tolerance to chytrid fungal disease in amphibians to improve conservation
  Dr L Grogan, Dr DN Newell, Prof H McCallum
Application Deadline: 23 September 2019

Funding Type

PhD Type

This PhD project will involve working with captive animals (endangered Fleay’s barred frogs and tadpoles) to understand host responses to infection and mechanisms of resistance and tolerance to the devastating fungal disease, frog chytridiomycosis.
  Role of pentraxin and interaction with complement in immune defence against opportunistic infections
  Prof C Garlanda, Prof S Meri
Application Deadline: 10 November 2019

Funding Type

PhD Type

PTX3 is a soluble pattern recognition molecule which acts as a key component of humoral innate immunity in opportunistic infections of fungal and bacterial origin.
  The human heart in health and disease, one cell at a time
  Dr M Noseda
Application Deadline: 20 September 2019

Funding Type

PhD Type

3-year NHLI-funded PhD post – starting October 2019. Applications are invited from candidates with a Master’s degree (Merit and above) in Biomedical Sciences, Immunology or a related discipline, for a 3 year PhD.
  Generation, characterisation and commercialisation of native-restricted and neoepitope-specific monoclonal antibodies directed against the terminal complement protein C7
  Prof R Würzner, Prof Z Prohaszka
Application Deadline: 10 November 2019

Funding Type

PhD Type

Complement is one of the most important players in innate immune defense. Three activation pathways are triggered by multiple interactions and are amplified in cascades, leading to the activation of the terminal complement (TC) pathway.
  Analysing the skin response to various pollutants, with a focus on immune response by using 3D organotypic cultures generated with human cells
  Dr S Dubrac
Applications accepted all year round

Funding Type

PhD Type

This PhD position builds upon previous work, published by the host Laboratory at the Medical University of Innsbruck (Austria), suggesting a link between pollution and atopic dermatitis (eczema).
  Exercise and nutritional status on metabolic factors, hormonal responses and inflammation in women
  Dr J Allgrove
Applications accepted all year round

Funding Type

PhD Type

Obesity is a major risk factor for chronic diseases such as type 2 diabetes, adverse cardiovascular events and metabolic syndrome-related disorders.
  Potential therapeutic effects of natural products in Human Papillomavirus (HPV) related cervical cancers
  Dr H Ashrafi
Applications accepted all year round

Funding Type

PhD Type

Cervical cancer is one of the most common types of cancer affecting women worldwide. Infection caused by high-risk human papillomaviruses (HPVs), especially type 16 and 18 are implicated in the etiology of most cervical cancers.
  Sex differences of ultra-endurance running: Profiling of female ultra-runners
  Dr H Moir
Applications accepted all year round

Funding Type

PhD Type

Ultra-endurance running has become increasingly popular, both in amateur and recreational athletes, with an exponential increase in the number of ultra-marathon finishers between 1998 and 2011 (Cejka et al., 2013; Hoffman & Krishnan 2013;).
  Innate immune control of virus infection
  Assoc Prof K Helbig
Applications accepted all year round

Funding Type

PhD Type

Viruses infect all living organisms, and our laboratory studies the early host response to viral infections in humans, and other mammalian and non-mammalian animal hosts.
  The influence of psychological stress on health and physical performance in British Army Recruits
  Prof N Walsh
Application Deadline: 30 September 2019

Funding Type

PhD Type

PhD Studentship (4 years). Applications are invited for a four-year, full-time PhD studentship supervised by Prof Neil Walsh and his team in the School of Sport and Exercise Sciences, Liverpool John Moores University.
  Investigating the regulation of the RNA modifying enzyme ADAR1 and how it regulates other biological pathways and diseases
  Dr M O'Connell, Dr L Keegan, Dr JN Nováček
Application Deadline: 31 October 2019

Funding Type

PhD Type

The ADAR enzymes convert adenosine into inosine in dsRNA. Inosine is one of the most abundant and best studied modifications found in different classes of RNA.
  Some like it hot: how mismatch between host and pathogen thermal ecology influences adaptation to global change
  Dr M Hall
Applications accepted all year round

Funding Type

PhD Type

Global change is predicted to result in both rapidly changing environments and dramatic changes in disease outbreaks. Key to predicting winners and losers under the nexus of infection and global change is any mismatch between hosts and pathogens in their thermal tolerances and adaptive potential.
  Common severe childhood infections, innate inflammatory responses and cardiometabolic risk: The VASCular changes aFter INfectious Diseases (VASCFIND) study
  Prof D Burgner, Dr S Bekkering
Applications accepted all year round

Funding Type

PhD Type

SUMMARY. Infection, the commonest reason for childhood hospital admission, is a major driver of inflammation and is associated with cardiometabolic risk and disease.
  The role of endogenous retroviruses in human health and disease
  Dr G Magiorkinis
Applications accepted all year round

Funding Type

PhD Type

More than 10 years have passed since the first high quality (nearly) complete version of the human genome and we are still exploring its functionality.
  The feasibility of in situ VOC analysis on icy bodies
  Dr S Sheridan, Dr V Pearson, Prof M Patel, Dr G Morgan
Application Deadline: 30 September 2019

Funding Type

PhD Type

This project will conduct a feasibility study of potential instrumentation that could be deployed on future missions to icy moons.
  Using T cells to eradicate cancer
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in immuno-oncology and the development of novel immunotherapeutic approaches for the treatment of cancer.
  Evaluation of natural plant based botanicals as alternative to therapeutic antibiotics
  Dr C Situ
Applications accepted all year round

Funding Type

PhD Type

It has become widely recognised that antimicrobial resistance (AMR) is one of the biggest health threats that mankind faces encompassing huge health and economic burdens on governments and societies in every region of the globe.
  Strategies to improve the safety and efficacy of Chimeric Antigen Receptor (CAR) T cell therapy
  Dr S Tey, Assoc Prof T Kenna
Application Deadline: 20 September 2019

Funding Type

PhD Type

Our laboratory studies the interaction between the immune response and tumour control, with a particular emphasis on translating our ever-expanding basic science knowledge into clinically applicable therapeutic platforms.
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