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University of Birmingham, Institute of Metabolism and Systems Research PhD Projects

We have 10 University of Birmingham, Institute of Metabolism and Systems Research PhD Projects

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  Adipose tissue functional responses to nutritional stress
  Dr K Manolopoulos, Prof D Calebiro
Applications accepted all year round

Funding Type

PhD Type

Obesity is the leading cause of insulin resistance and type 2 diabetes. Adipose tissue dysfunction has been proposed as being central in the pathophysiology of obesity-related complications.
  Determining the translational potential of the highly phosphorylated proto-oncogene PBF
  Dr V Smith
Applications accepted all year round

Funding Type

PhD Type

In order to translate the many molecular alterations now detectable in human tumours into effective clinical management we need to fully understand their impact on tumour biology.
  Development of novel artificial intelligence algorithms for network wide metabolic flux analysis with stable isotope tracers
  Dr C Ludwig, Dr S He
Applications accepted all year round

Funding Type

PhD Type

The efficient function of the metabolic network in eukaryotic cells relies on its separation into a number of closely-linked but metabolically distinct compartments.
  Global Maternal Health
  Dr D Lissauer, Prof A Coomarasamy
Applications accepted all year round

Funding Type

PhD Type

This PhD would be based within the WHO Collaborating Centre for Global Maternal Health, within the Institute of Metabolism and Systems Research at the University of Birmingham.
  Metabolic control of T cell function
  Dr S Dimeloe
Applications accepted all year round

Funding Type

PhD Type

Current research interests in Sarah Dimeloe’s lab focus on the metabolism and interlinked immune function of T lymphocytes in health and disease.
  Polo-like kinase inhibitors for targeted therapy in adrenocortical carcinoma
  Dr C L Ronchi, Dr P Foster
Applications accepted all year round

Funding Type

PhD Type

Adrenocortical carcinoma (ACC) is a rare cancer with a generally poor prognosis and partially unknown pathogenesis.
  Repairing DNA Damage in Response to BRAF Mutation
  Dr C McCabe, Prof G Stewart
Applications accepted all year round

Funding Type

PhD Type

We are the leading thyroid cancer research group in the UK; we work on other neoplasias as well, including breast and head and neck etc.
  Targeting steroid metabolism to block colorectal cancer proliferation
  Dr P Foster, Dr L Cox
Applications accepted all year round

Funding Type

PhD Type

Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds.
  Targeting the Role of Myeloid Steroid Metabolism in Chronic Inflammation
  Dr R Hardy, Dr P Foster
Applications accepted all year round

Funding Type

PhD Type

Background. Myeloid derived cell populations such as macrophages play a critical role in the early innate immune response, whilst dendritic cells are essential in bridging the progression to an adaptive immune response.
  Vitamin D and immunometabolism
  Prof M Hewison, Dr S Dimeloe
Applications accepted all year round

Funding Type

PhD Type

Vitamin D has potent anti-inflammatory and antibacterial immune effects.
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