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We have 241 PhD Research Projects PhD Projects, Programmes & Scholarships in Leeds

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PhD Research Projects PhD Projects, Programmes & Scholarships in Leeds

We have 241 PhD Research Projects PhD Projects, Programmes & Scholarships in Leeds

University of Bradford

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University of Leeds

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Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

University of Leeds Faculty of Medicine and Health
Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more
 Supervisors: Dr F Errington-Mais, Dr V Jennings
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genetics: Unravelling the Norrin/beta-catenin signaling pathway and its role in retinal angiogenesis and blindness

University of Leeds Faculty of Medicine and Health
Our previous work on the genetic analysis of individuals with the inherited retinal disease Familial Exudative Vitreoretinopathy (FEVR), has helped identify a new angiogenesis pathway, the Norrin/beta-catenin pathway. Read more
 Supervisors: Dr C Toomes, Dr J Bond, Dr S Bell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Complex 3D modelling of the tumour microenvironment for immunotherapy combination screening

University of Leeds Faculty of Medicine and Health
Cancer immunotherapy holds significant promise for the treatment of a range of cancers. Read more
 Supervisors: Dr MA Volpato, Dr F Errington-Mais
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Virology: Unique Antiviral Therapy targeting Zika and Related Viruses

University of Leeds Faculty of Medicine and Health
Zika Virus (ZIKV) has emerged as a new mosquito-borne threat to public health after the devastating South American outbreak. Read more
 Supervisors: Dr S Griffin, Dr A Kalli, Dr C McKimmie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Virology: Sun exposure as a novel risk factor for Zika virus infection

University of Leeds Faculty of Medicine and Health
Mosquito-borne disease is now receiving unprecedented attention due to major outbreaks in new geographic areas including Brazil, Mexico, India, China, the Middle East and SE Asia. Read more
 Supervisors: Dr C McKimmie, Dr K Shams, Dr S Griffin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity

University of Leeds Faculty of Medicine and Health
The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more
 Supervisors: Dr M Lorger, Dr R Salmond
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Immunotherapy: Killing Cancer using Dead Virus

University of Leeds Faculty of Medicine and Health
It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more
 Supervisors: Dr S Griffin, Dr A Samson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Haematology: Oncogenic reprogramming of immune cells

University of Leeds Faculty of Medicine and Health
Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory. Read more
 Supervisors: Dr F Errington-Mais, Dr P Laslo
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

University of Leeds Faculty of Medicine and Health
The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more
 Supervisor: Dr M Ali
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genetics: Genetic studies of developmental eye disorders to investigate genotype-phenotype correlations

University of Leeds Faculty of Medicine and Health
Developmental eye defects that affect the front of the eye give rise to a spectrum of congenital ocular phenotypes that affect the cornea, lens, iris, trabecular meshwork or the globe itself. Read more
 Supervisor: Dr M Ali
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

University of Leeds Faculty of Medicine and Health
Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more
 Supervisors: Prof M Wilcox, Prof A O'Neill, Dr J Freeman, Dr I Moura
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Why and how do brain tumour cells invade ‘mini-brains’?

University of Leeds Faculty of Medicine and Health
Globally, nearly 189,000 people die each year as a result of brain cancer and around 250,000 people are diagnosed with a malignant brain tumour (umbrella name. Read more
 Supervisors: Dr H Wurdak, Dr R Mathew
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Repurposing drugs as new treatments for breast cancer

University of Leeds Faculty of Medicine and Health
Breast cancer (BC) is the most common cancer, with over 1 million new cases diagnosed worldwide each year. For some types of BC, hormonal treatments have been very effective but one particular BC subtype, triple negative breast cancer (TNBC), is highly aggressive and lacks a targeted therapy. Read more
 Supervisors: Dr L Matthews, Dr P Meakin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Inhibiting cell metabolism to enhance tumour cell death

University of Leeds Faculty of Medicine and Health
All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more
 Supervisors: Dr S Papa, Dr R Tooze
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Biophotonic nanomaterials: developing new quantum dots and biomolecules towards a more complete use of the solar spectrum

University of Leeds Faculty of Engineering and Physical Sciences
Plants and other biological systems are a source of inspiration for nanotechnology and solar energy research because the early stages of photosynthesis have high quantum efficiency. Read more
 Supervisors: Dr P.G. Adams, Dr K Critchley
 28 June 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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