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Biophysics PhD Projects in Leeds

We have 8 Biophysics PhD Projects in Leeds

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Showing 1 to 8 of 8
  Inhibition of a protein-protein interaction mediating antibiotic resistance
  Dr J.H. Tomlinson, Prof A J Wilson
Application Deadline: 1 May 2019
The dramatic rise in antibiotic resistance is threatening our ability to treat bacterial infections and precipitating a public health crisis.
  Plague hazard assessment toolset
  Prof C Molina-París
Applications accepted all year round
The pathogen of interest in this project is Yersinia pestis, a gram-negative bacterium and the causative agent of plague, a disease of humans and mammals which has been recognised since antiquity.
  How cells respond to stress: The role of chaperone post-translational modifications in health and disease
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A Zhuravleva, Prof R.W. Bayliss
Application Deadline: 1 May 2019
The Hsp70 chaperones are key cellular molecular machines that protect organisms from the toxic consequences of environmental and pathological stresses.
  Rational design and production of glyco-peptidic inhibitors of pathogens’ adhesion to host cells.
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E Paci, Prof W B Turnbull
Application Deadline: 30 September 2019
The ability of protein molecules to stick to cells is crucial for life and disease. The project is based on a novel concept to design adhesive molecules based on multivalence and entropic stabilisation.
  Pattern Formation (Applied Nonlinear Dynamics): understanding the formation and stability of complex patterns such as quasipatterns, spatio-temporal chaos or turbulent spirals
  Prof A M Rucklidge
Applications accepted all year round
Regular patterns, such as stripes, squares and hexagons, are ubiquitous in nature, and their formation and stability are governed by the intricate and complex interactions of symmetry and nonlinearity.
  Skyrmions under strain
  Research Group: Condensed Matter
  Dr T A Moore
Application Deadline: 3 May 2019
There has been an explosion of interest in skyrmions in recent years, with the very first x-ray images of skyrmion dynamics being released recently.
  An integrated approach to the study of cellular interactions with amyloid
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford
Applications accepted all year round
The formation of insoluble amyloid fibrils is associated with a spectrum of human disorders, the amyloidoses, which include Alzheimer’s, Parkinson’s, type 2 diabetes and dialysis related amyloidosis (DRA).
  Development and characterisation of synthetic ion channel binding proteins.
  Research Group: School of Biomedical Sciences
  Dr J D Lippiat, Dr D Tomlinson
Applications accepted all year round
We are developing methods to identify novel proteins, Affimers, that recognise extracellular domains of ion channels. These have applications in various aspects of biology, from tools to visualise the location and distribution of ion channels in native tissue, to novel modulators of ion channel function.
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