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Imperial College London Featured PhD Programmes
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Biotechnology PhD Research Projects in Leeds

We have 29 Biotechnology PhD Research Projects in Leeds

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Leeds  United Kingdom

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We have 29 Biotechnology PhD Research Projects in Leeds

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Accurate and Ultra-Sensitive DNA Mutation Detection by Nanopore Barcode Recording

Mutations of DNA within the genome are defining features of cancers, yet their accurate, quantitative, multiplexed detection with amplification-based methods is only possible above a threshold of tumour burden where sufficient material is available. Read more

Identification and characterisation of genes in a model alga required for robust growth and nutrient uptake on waste water

In this interdisciplinary project between the Schools of Molecular and Cellular Biology and Civil Engineering, we aim to deliver an environmental biotech solution (P-remediation with algae) through an investigative algal molecular biology approach. Read more

Health Opportunity for Patient Empowerment in Gestational Diabetes (HOPE-GDM)

  Research Group: Chemistry and Biosciences
Gestational Diabetes is a temporary condition diagnosed at 24-28 weeks gestation, where the body is unable to maintain normal blood glucose levels due to insulin resistance during pregnancy. Read more

Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

  Research Group: School of Molecular and Cellular Biology
V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves the breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more

2D and 3D crowd steering analysis in virtual reality

  Research Group: School of Computing
This project aims to investigate crowd behaviours under emergencies. Crowd emergency and evacuation simulation has been a central topic in several fields including crowd simulation, design and safety. Read more

2D and 3D crowd analysis and simulation using deep learning and big data analysis

  Research Group: School of Computing
Every future city will have a digital `twin' that consumes data from the physical city and generates predictions for its design, construction, and management. Read more

3D Human Motion Analysis

  Research Group: School of Computing
Human motion is deceivingly simple but intricately complicated. We walk, run and jump on a daily basis without realising how much time and effort we made to master these motor skills when we were little. Read more

Pushing the Resolution Limits of High-Speed Atomic Force Microscopy

  Research Group: School of Physics and Astronomy
Understanding the structural dynamics of complex molecules is vital to advancing our knowledge of materials, medicine and diseases, yet there are few techniques which can capture motions at high enough speeds or resolution to understand the underlying behaviour. Read more

Cellular logistics: Biological physics of selective protein and gene transport across the nuclear envelope

  Research Group: School of Physics and Astronomy
The coordinated transport of proteins and nucleic acids between the nucleus and the cytosol is vital for proper gene expression and cell function, and hijacked by viruses to propagate. Read more

Biological physics of cell trafficking: Immune cell homing at the blood vessel wall

  Research Group: School of Physics and Astronomy
Cell trafficking is vital to all multicellular life and key in diseases such as cancer. In this PhD project, you will devise new methods to study how immune cells that circulate in the blood stream find and bind to sites of inflammation and how cancer cells hijack the system to metastasize. Read more

Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more

Immunotherapy: Killing Cancer using Dead Virus

It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more

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