Cancer Biology PhD Research Projects PhD Projects, Programmes & Scholarships in Leeds

Year round applications PhD Research Project Self-Funded PhD Students Only

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisor: Dr A Garvin

How does the E5 oncoprotein contribute to human papillomavirus replication and disease?

Supervisors: Dr A Macdonald, Prof A Whitehouse

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

New Drugs for Brain Tumours: A Locoregional Implant Brain Tumours

Supervisors: Dr R Wheelhouse, Prof A Paradkar, Dr S Shnyder

Research Group: Medicines Development and Pharmaceutical Sciences

Next-generation temozolomide derivatives for the treatment of high-grade glioma have been developed at the University of Bradford. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Development of antibody-drug conjugates (ADCs) for oncology indications

Supervisors: Prof K Pors, Dr Muhammad Wahajuddin, Prof R Falconer

Research Group: Institute of Cancer Therapeutics

A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Leeds Faculty of Medicine and Health

Haematology: Oncogenic mechanisms causing malignant transformation of B cells and plasma cells

Cancers of B cells and plasma cells, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Read more

Supervisor: Prof U Klein

Year round applications PhD Research Project Self-Funded PhD Students Only

New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala

Research Group: Medicines Development and Pharmaceutical Sciences

The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Understanding perspectives of prehabilitation in underserved cancer populations: A qualitative study to inform service design and delivery.

Supervisors: Dr S Burke, Dr CB Burnett, Dr KNF Franks

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Structural and mechanistic studies of fibroblast growth factor receptor signalling

Supervisors: Prof A.L. Breeze, Prof F. Sobott

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

University of Leeds Faculty of Medicine and Health

NIHR Leeds BRC: The microbiome and the promotion of bowel cancer: The key to understanding causation and prevention of this important disease

Bowel cancer is the second commonest cause of cancer death in the UK and affects 1.9 million people annually worldwide. Its cause is still unknown but recent work by Wood et al. Read more

Supervisors: Dr K Marks, Dr H Wood, Dr N West, Prof P Quirke

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

University of Leeds Faculty of Medicine and Health

NIHR Leeds BRC: Multimodal predictive modelling of outcome in patients with gastrointestinal cancer

Worldwide, cancer of the upper (oesophagus, stomach) and lower gastrointestinal (colon and rectum) tract is newly diagnosed in 3.6 million patients every year and 2.2 million patients die from this disease every year. Read more

Supervisors: Dr H Grabsch, Dr N West, Dr D Magee

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

Supervisors: Dr T Nasim, Dr M Najafzadeh

Research Group: Pharmacology and Experimental Therapeutics

Myelodysplastic syndromes (MDS) are a type of blood cancer where the patients do not have enough healthy blood cells. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Polysialyltransferases as a target in metastatic cancer

Supervisors: Prof R Falconer, Dr S Shnyder

Research Group: Institute of Cancer Therapeutics

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Nanoparticle synthesis and application in magnetic field hyperthermia for cancer therapy

Supervisors: Dr P Drake, Dr S Shnyder

Research Group: Chemistry and Biosciences

Magnetic field hyperthermia (MFH) is currently undergoing clinical trials for use in humans. The research to date has shown the effectiveness of the approach in cells and animal models and the initial results from human trials are promising. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Exploring the role of interferon stimulated genes (ISGs) in stem cells of serous ovarian cancer

Supervisors: Dr S Swaroop, Dr G Grimaldi, Dr ED Perkins

Research Group: Institute of Cancer Therapeutics

Epithelial ovarian cancer (EOC) is the leading cause of mortality in women due to gynaecological cancers. High-grade serous ovarian cancer (HGSOC) accounts for 70-80% of patients with EOC. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only

Evaluating Photodynamic Therapy in colorectal cancer using patient-derived organoids

Supervisors: Dr MI Khot, Prof A Paradkar, Prof D Jayne

Research Group: Chemistry and Biosciences

Colorectal cancer (CRC) is the 3rd most common cancer worldwide. Surgery is first line treatment and often in adjunct with chemotherapy. Read more

Year round applications PhD Research Project Self-Funded PhD Students Only