We have 106 PhD Research Projects PhD Projects, Programmes & Scholarships in Leicester

Malignant pleural mesothelioma is a rare, incurable cancer that carries a dismal prognosis. Its incidence is increasing globally despite its primary cause, asbestos exposure, having been known for over 50 years. Read more

Supervisor: Prof E Hollox

Year round applications PhD Research Project Self-Funded PhD Students Only

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Symbols of power, prestige goods or vibrant materials? Rethinking gold, jet and amber grave goods in Early Bronze Age Britain.

University of Leicester Archaeology and Ancient History

The project forms one strand of the Leverhulme Funded Research Leadership Award, A New History of Bronze. This project explores how the emergence and use of copper and bronze metalworking in this period created new possibilities for crafting, leadership and violence. Read more

Supervisor: Dr R Crellin

21 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Ground stone in a metallic world

University of Leicester Archaeology and Ancient History

Supervisor: Dr R Crellin

21 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Agricultural genomics, chromosomes, genome and repetitive sequence evolution in crops, farm animals, models and wild relatives

University of Leicester Department of Genetics and Genome Biology

In this project, you will investigate the large-scale organization of an agricultural species and its wild relatives. We will use genomic data from DNA sequencing, including methylation where appropriate. Read more

Supervisor: Prof P HESLOP-HARRISON

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Functional effects of variable number tandem repeat expansions in idiopathic pulmonary fibrosis

University of Leicester Department of Genetics and Genome Biology

Research Group: Human & Medical Genetics

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by the formation of scar tissue in the lungs. Read more

Supervisor: Prof E Hollox

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the role of mucin genetic variation in lung disease

University of Leicester Department of Genetics and Genome Biology

Research Group: Human & Medical Genetics

Understanding how genetic variation contributes to lung diseases is important in understanding how the disease develops and identifying potential molecular targets for therapy. Read more

Supervisor: Prof E Hollox

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

University of Leicester Molecular and Cell Biology

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

Supervisor: Dr G Hall

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural insights into genome control by cohesin

University of Leicester Molecular and Cell Biology

Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more

Supervisor: Prof D Panne

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural and functional analysis of the protein complexes which regulate cell fate decisions to identify novel cancer therapies

University of Leicester Molecular and Cell Biology

Whether a cell dies or not has profound consequences on health and disease. In healthy tissue, cells that acquire high levels of genetic damage are safely removed via a process of programmed cell death. Read more

Supervisor: Dr JF Fox

Year round applications PhD Research Project Self-Funded PhD Students Only

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Transcriptional kinases in cancer and developmental disorders

University of Leicester Molecular and Cell Biology

Cyclin-dependent kinases (CDKs) are protein kinases performing essential functions in regulation of cell cycle and transcription. Read more

Supervisor: Dr MT Tellier

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural investigation of oncogenic splicing factors

University of Leicester Molecular and Cell Biology

More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more

Supervisors: Dr C Dominguez, Prof I Eperon, Prof A Hudson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Obtaining an integrated understanding of oncogenic RAS signalling

University of Leicester Molecular and Cell Biology

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. The physiological importance of RAS signalling is evident as about 25% of all human cancers harbour mutations in ras genes, where kras is most frequently mutated (about 18%) (COSMIC, v94). Read more

Supervisor: Dr K Tanaka

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases

University of Leicester Molecular and Cell Biology

Ageing is a biological process that affects all humans. Despite the scientific advances of the past decades, the mechanisms that lead to ageing are not fully understood. Read more

Supervisor: Prof S Macip

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the roles that G protein coupled receptors play in hypertension

University of Leicester Molecular and Cell Biology

G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more

Supervisor: Dr J Willets

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer biology: identification of new treatment options for EML4-ALK driven lung cancer through understanding mechanisms of cell division and migration.

University of Leicester Molecular and Cell Biology

Lung cancer is the largest cause of cancer-related deaths in the UK and worldwide. While little progress has been made in long-term survival rates, we now have a good understanding of the genetic drivers raising the prospect of earlier diagnosis and more effective treatments. Read more

Supervisor: Prof A Fry

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 106 PhD Research Projects PhD Projects, Programmes & Scholarships in Leicester

PhD Research Projects PhD Projects, Programmes & Scholarships in Leicester

We have 106 PhD Research Projects PhD Projects, Programmes & Scholarships in Leicester

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