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Cell Biology / Development PhD Projects in Leicester

We have 28 Cell Biology / Development PhD Projects in Leicester

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Showing 1 to 10 of 28
  PhD scholarship for biological applications in multifunctional materials manufacturing
  Dr C Torres-Sanchez
Application Deadline: 14 May 2019
PhD Studentship. Porosity tailored titanium scaffolds for bone engineering. Reference number. CTS2019. Start date of studentship.
  Clock gene polymorphisms in Drosophila; natural selection and function
  Prof C P Kyriacou, Dr E Rosato
Application Deadline: 5 May 2019
The molecular function of circadian clock genes are well understood and conserved from flies to mammals, but the implications of natural variation in clock gene sequences are only recently becoming evident.
  Heme regulation of signalling at potassium channels in the cardiovascular system
  Dr N Storey, Dr N W Davies
Application Deadline: 5 May 2019
Ion channels in the smooth muscle of the cardiovascular system control blood pressure and cardiac contractility through changes in their membrane potential.
  Molecular mechanisms underpinning EML4 driven microtubule stabilization and cell migration
  Prof A M Fry, Prof K Brown
Application Deadline: 5 May 2019
EML4 is a poorly characterised microtubule-associated protein [1]. The purpose of this cell biology-focused PhD project is to explore the molecular mechanisms through which EML4 regulates microtubule dynamics and cell migration.
  How does nucleosome remodelling silence chromatin?
  Dr T Schalch, Dr S Cowley
Application Deadline: 5 May 2019
Regulation of transcription through chromatin architecture is governed by nucleosome remodelers and is essential in establishing the transcriptional programs of eukaryotic cells, which underpin survival, cellular identity and many disease states.
  Structural mechanism of signal-dependent gene transcription
  Prof D Panne, Dr A Revyakin
Application Deadline: 5 May 2019
The control of gene transcription is one of the main regulatory steps for cellular gene regulation.
  Ameliorating ageing and age-related diseases by targeting senescent cells
  Dr S Macip, Dr S Cowley
Application Deadline: 5 May 2019
Ageing is a process defined by the accumulation of old (senescent) cells in tissues. It has been shown that senescent cells interfere with the normal functions of organs and thus lead to the normal phenotypic changes associated with ageing as well as the establishment of age-related diseases.
  Exploring the boundaries of the human acetylome
  Dr S Cowley, Prof D Panne
Application Deadline: 5 May 2019
Lysine acetylation (Lys-Ac) is an abundant post-translational modification (PTM) occurring on thousands of proteins. However, our understanding of ‘acetylome’ regulation and its functional consequences remains well behind other common PTMs such as phosphorylation and ubiquitination.
  Obtaining mechanistic insights into interplay of multiple RAS effectors in a model system
  Dr K Tanaka, Dr C Dominguez
Application Deadline: 5 May 2019
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. Importantly, about 20% of all human cancers harbour mutations in RAS genes (COSMIC).
  Network interactions shape the circadian clock in Drosophila melanogaster
  Dr E Rosato, Prof C P Kyriacou
Application Deadline: 5 May 2019
The circadian clock is an endogenous mechanism that synchronizes almost all behaviour and physiology with the Earth’s 24 hour environmental cycles.
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