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Structural Biology PhD Projects in Leicester

We have 4 Structural Biology PhD Projects in Leicester

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Showing 1 to 4 of 4
  How does nucleosome remodelling silence chromatin?
  Dr T Schalch, Dr S Cowley
Application Deadline: 6 January 2019
Regulation of transcription through chromatin architecture is governed by nucleosome remodelers and is essential in establishing the transcriptional programs of eukaryotic cells, which underpin survival, cellular identity and many disease states.
  Molecular mechanisms of transcriptional regulatory complexes
  Prof J Schwabe
Applications accepted all year round
The regulation of gene expression is fundamental to all stages of life. In appropriate or failure of in this regulation is a major cause of disease including cancers and metabolic diseases.
  Bacterial sensory perception: investigating the stimuli that bacteria can sense and how this information is used to regulate bacterial behavior
  Dr H O'Hare
Applications accepted all year round
Bacteria sense numerous environmental stimuli and integrate this information to regulate their own cellular processes accordingly.
  How do antibiotic-producing bacteria decide when to synthesise antibiotics, and how much to make?
  Dr H O'Hare, Dr G Mukamolova
Applications accepted all year round
Actinobacteria are well-known as secondary metabolite producers and hence are of high interest commercially for drug discovery and for production of agrochemcials and human and animal therapeutics.
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