Development of CRISPR-Cas and LAMP diagnostics to inform plant disease management
Dr J Tovar, Dr L Bindschedler
15 February 2019
Fungal infections are a major threat to food security worldwide. In the UK alone, Septoria wheat leaf blotch – a fungal disease caused by Zymoseptoria tritici – and oilseed rape phoma leafspot and stem canker, diseases caused by the fungi Leptosphaeria maculans and L.
How to fix a broken heart - The next frontier: from cell to cage side treatment
Dr D Connolly, Prof D Werling, Dr J Dudhia
10 February 2019
Dilated Cardiomyopathy (DCM) is a common and serious disease, which imposes a significant welfare burden in dogs. DCM is particularly well characterise in Dobermans where a 58.8% cumulative prevalence has been identified in European lines.
Development of gene therapies for muscular dystrophies
Dr L Popplewell
Applications accepted all year round
The activities in the Popplewell lab focus on the development of pre-clinical gene therapies for neuromuscular diseases, in particular muscular dystrophies based on gene replacement, endonuclease-mediated gene editing, antisense oligonucleotide (AO)-induced exon skipping and gene sliencing.