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Medical / Clinical Science PhD Research Projects

We have 69 Medical / Clinical Science PhD Research Projects

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Biological & Medical Sciences

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We have 69 Medical / Clinical Science PhD Research Projects

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Identification of determinants of sudden cardiac death using population studies

Sudden cardiac death is a major cause of deaths from cardiovascular origin. Indeed, up to half of the deaths from cardiovascular diseases are caused by sudden cardiac death. Read more

Does SUMO protease SENP3 play a role in α-synuclein aggregation and toxicity?

Pathogenic causes for progressive loss of dopaminergic neurons along with protein aggregates termed Lewy bodies in the substantia nigra in (SN) Parkinson’s disease (PD) are not yet understood. Read more

Role for deSUMOylation Enzyme SENP3 in the Regulation of Pexophagy Linked to Peroxisomal Biogenesis Disorders

Peroxisomal Biogenesis Disorders (PBDs) such as Zellweger syndrome (1) refers to a group of diseases caused by genetic mutations in one of the membrane proteins (PEXs) responsible for biogenesis of the peroxisomes. Read more

Application of animal corneal cells for skin regeneration, tissue engineering and wound healing enhancement

  Research Group: Centre for Skin Sciences
Engineering of biological skin substitutes has progressed over the years from individual applications of skin cells, or biopolymer scaffolds, to combinations of cells and scaffolds for treatment, healing, and closure of acute and chronic skin wounds. Read more

Ankle moment contribution in everyday tasks: effects of ageing

  Research Group: Medical Engineering
There is a fall on stairs every 90 seconds in the UK, and an estimated 250,000 non-fatal accidents which are serious enough to merit a trip to A&E. Read more

Re-purposing established drugs for the resolution of pulmonary arterial hypertension (PAH)

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Therapeutic resolution of pulmonary arterial hypertension (PAH) by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Characterizing novel molecular targets for genome-informed precision cancer medicine

Ovarian cancer is a leading cause of cancer death in women. Identification of novel, actionable and effective strategies to treat the disease could significantly contribute to the improvement of patient survival. Read more

Expanded potential stem cells for regenerative medicine, immunotherapy, and biotechnology

Embryonic stem cells (ES cells) and induced pluripotent stem cells (iPS cells) are pluripotent and thus hold great promise in regenerative medicine, studying disease mechanisms and drug discovery. Read more

Extracellular matrix remodeling in neuromuscular synapse development

Motor neurons, skeletal muscles, and perisynaptic Schwann cells interact with extracellular matrix (ECM) to form the tetrapartite synapse in the peripheral nervous system. Read more

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