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Medical / Clinical Science PhD Research Projects

We have 69 Medical / Clinical Science PhD Research Projects

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We have 69 Medical / Clinical Science PhD Research Projects

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Integrated chemical biology approach to study cellular redox signaling and its associated diseases

Redox-active compounds, which can undergo oxidation/reduction readily, were once classified as detrimental compounds in biology and known to contribute to serious diseases such as cancer, obesity, diabetes and neurodegenerative disorders. Read more

Method development and application of single cell technologies

Single cell technologies have gained immense popularity in the recent past. There has been major technological advancement in how to efficiently capture individual cells in a high throughput manner. Read more

Single-cell lineage maps of blood/immune cells in human organoids

Blood/immune cells sustain life through oxygen supply, resistance to infection, and gatekeeping cancer cells. We developed a powerful stem cell culture system that allowed us to recapitulate blood/immune cell development in human organoids. Read more

Towards Defining DNA Damage Detection and Repair Control

Research Interest. DNA repair is fundamental to life. Failing to launch DNA repair in the right place at the right time leads to a wide range of devastating human diseases, including cancers and developmental disorders. Read more

Dissecting the mechanisms of T-lymphocytes affect liver stem cell activation

Research interests/description of main research theme. Despite having great regenerative capacity, the liver fails to regenerate during chronic liver disease due to impaired hepatocyte proliferation. Read more

Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks

The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children. Read more

The development of Rab27 inhibitors for treatment of cancer cell invasion and proliferation

Rab27 small GTPases regulate movement and exocytosis of secretory granules in cell types including; melanocytes (melanosomes), T lymphocytes (lytic granules), granulocytes (azurophilic granules) and mast cells [1]. Read more

Inflammatory Arthritis in Childhood: Impact, Outcomes and Safety of Treatment

Juvenile Idiopathic Arthritis is the most common inflammatory arthritis of childhood. Although less common than arthritis in adults, a diagnosis of arthritis in a child can have lasting impacts on that child and their families through their entire lifespan. Read more

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