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Microbiology PhD Research Projects

We have 415 Microbiology PhD Research Projects

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We have 415 Microbiology PhD Research Projects

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Engineering enhanced vitamin synthesis in bacteria (WARRENM_Q22CASE)

This project aims to apply synthetic biology and metabolic engineering strategies to one of the most complex biochemical pathways found in nature in order to address a current need for a cheaper and more reliable source of vitamin B12, the so-called anti-pernicious anaemia factor. Read more

Molecular structuring of foods to feed the gut microbiome (WARRENF_Q22CASE)

Developing the latest generation of foods requires detailed structural and chemical insights into the molecular scale structuring within a food, as well as the application of novel processing methods. Read more

Location location location - how genome position affects gene expression (WEBBER_Q22DTP)

Bacterial genomes have evolved over billions of year to allow efficient expression of the right genes at the right times. It has become clear that the same gene, placed in different locations around a bacterial chromosome can display very different levels of expression. Read more

Are bacteria building toxic biofilms in your gut? (NARBAD_Q22DTP2)

Think of a corroded pipe. Now think of an inflamed gut. These conditions may be caused by similar bacteria. Sulphate reducing bacteria (SRB) are anaerobic bacteria, common in the environment and the gastrointestinal tract. Read more

Can we use bacteriocins to improve gut health? (NARBAD_Q22DTP1)

Many bacteria produce antimicrobial compounds to help them compete in mixed communities. Antimicrobial peptides called bacteriocins from food and dairy strains have already been exploited successfully to prevent food poisoning or mastitis. Read more

How do cells keep the pease? Resolving the conflict between DNA replication and transcription (NIEDUSZYNSKI_E22DTP)

At the heart of every cell a conflict is taking place, as the machinery of DNA replication and transcription clash. The conflict is over a specific sequence of DNA, which can only be engaged in either transcription or replication at any one time. Read more

Finding needles in haystacks: sequencing single bacteria from complex microbiomes (MACAULAY_E22DTP2)

Microbiomes are integral to many of the fundamental processes affecting society – from healthcare to agriculture - but the complexity and diversity harboured within these microbiomes and the roles of individual cells/species in adaptation to new environments/stresses is still largely unexplored. Read more

Molecular mechanisms underlying plant-pathogen arms race (MA_S22DTP)

With the human population projected to reach 9.7 billion by 2050, the looming challenge of feeding the rapidly growing population is threatened by plant pathogens, which cause an estimated 13% loss in crop yield each year. Read more

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