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Molecular Biology PhD Research Projects

We have 436 Molecular Biology PhD Research Projects

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We have 436 Molecular Biology PhD Research Projects

Studying a PhD in Molecular Biology would provide you with the chance to guide your own research project. With a strong link to Cell Biology, Molecular Biology projects revolve around understanding the composition, structure, and interaction of molecules within the cell that control its function. These are generally laboratory-based projects.

What’s it like to do a PhD in Molecular Biology?

As a PhD student in Molecular Biology, you’ll develop extensive laboratory skills including DNA sequencing, expression cloning, gene knockout, and DNA or protein arrays. Your understanding of the range of techniques available to you will continually improve as you’ll read the latest publications in the field.

Some typical research topics in Molecular Biology include:

  • Understanding the role of a certain protein within a cell
  • Investigating DNA repair mechanisms and potential faults
  • Studying the difference in post-translational modifications in response to stimuli
  • Development of novel therapeutics
  • Investigating how proteins act differently in a disease
  • Studying DNA replication

A majority of Molecular Biology projects are proposed in advance by the supervisor and are advertised on the university website. Some of these projects are fully-funded by the university or a doctoral training programme, while others require you to self-fund.

Suggesting a project for yourself is uncommon in Molecular Biology, due to the challenge of finding funding to cover PhD and bench fees, as well as having to find a supervisor with suitable equipment and research interests to support your project.

Day-to-day, you’ll be in the laboratory preparing or conducting experiments, analysing previous data, creating figures, and writing up the results, alongside quick chats with your colleagues and supervisors about your work.

In the final year of your PhD, you’ll complete an original thesis of approximately 60,000 words in length and give an oral defence of this during a viva exam.

Entry requirements

The entry requirements for most Molecular Biology PhD programmes involve a Masters in a subject directly related to Biology, with at least a Merit or Distinction. If English isn’t your first language, you’ll also need to show that you have the right level of language proficiency.

PhD in Molecular Biology funding options

The research council responsible for funding Molecular Biology PhDs in the UK is the Biotechnology and Biological Sciences Research Council (BBSRC). They provide fully-funded studentships including a stipend for living costs, a consumables budget for bench fees and a tuition fee waiver. Students don’t apply directly to the BBSRC, you apply for advertised projects with this funding attached.

It’s uncommon for Molecular Biology PhD students to be ‘self-funded’ due to the additional bench fees. However, if you were planning to fund yourself it might be achievable (depending on your project) through the UK government’s PhD loan and part-time work.

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Antiviral innate immunity in the ASGARD archaea

  Research Group: Biomedical Sciences Research Centre
Project Description. Viruses are an important part of most environments on the planet. All living things are infected by viruses, and many different defence systems have evolved to combat infection. Read more

Textile Fibres from Recombinant Keratin Proteins

Applicants are invited to apply for a fully funded PhD programme to carry out a feasibility study to identify novel ways of producing recombinant keratin proteins and to produce sustainable textile fibers. Read more

PhD in Ion Channel Biology

  Research Group: Smooth Muscle Research Group
Dundalk Institute of Technology. -. PhD Studentship Smooth Muscle Research Centre (SMRC), Dundalk, Ireland. The Smooth Muscle Research Centre in Dundalk Institute of Technology, Ireland comprises a cross-disciplinary research team focused on the regulation of ion channels in health & disease. Read more

Understanding coronavirus interactions with host RNA regulation pathways

This is a fully funded 3.5 year PhD opportunity to investigate the biology of coronaviruses including SARS-CoV-2. During infection viruses commandeer host cell gene expression machinery to facilitate viral protein production. Read more

Rewiring cell signalling by targeted protein degradation and dephosphorylation

Post-translational modifications on proteins, such as reversible ubiquitylation and phosphorylation, are fundamental to controlling cellular signalling through regulation of protein stability and function. Read more

Molecular mechanisms underlying Parkinson's disease

There is great need for improved understanding of the mechanistic biology underlying Parkinson’s disease. Such knowledge will help with development of new drugs that slow or even halt the progression of the disease. Read more

PRIORITIZING DRUG COMBINATIONS IN LEUKEMIA BASED ON ANALYSIS OF TARGETTED THERAPY IN VIVO

The inhibition of BCR-associated kinases by so-called B cell receptor signalling inhibitors in B cell leukemia and lymphomas is a potent therapeutic strategy, and several BTK and PI3K kinase inhibitors are available for clinical use (Ondrisova and Mraz, 2020). Read more

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