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Molecular Biology PhD Research Projects

We have 927 Molecular Biology PhD Research Projects

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We have 927 Molecular Biology PhD Research Projects

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Accelerating fragment-based drug discovery using NMR spectroscopy

Applications must be complete, including both references, by 14th January 2022 at 5pm    . Fragment-based drug discovery (FBDD) is a widely used approach to generate starting points for drug discovery and tools for chemical biology [1]. Read more

The Soil Microbiome in Legume Rotations

Grain legumes (pulses) are an important arable break crop in the UK, fixing nitrogen through Rhizobia to benefit following crops, and providing a vital source of protein in food and feed. Read more

China Scholarship Council: Molecular mechanisms underlying Parkinson's disease

There is great need for improved understanding of the mechanistic biology underlying Parkinson’s disease. Such knowledge will help with development of new drugs that slow or even halt the progression of the disease. Read more

China Scholarship Council: Structural and membrane biology of polarized trafficking

Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more

China Scholarship Council: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells

The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation, and determine how protein kinase signalling is disrupted to cause human developmental disorders. . Read more

China Scholarship Council: Monitoring and manipulating kinase signaling in the context of polarity, immune signaling and cancer

Cell polarity is a central feature of most if not all cells across species. Polarity can be understood as the unequal distribution of molecules, organelles and other cellular features allowing cells to organise functions and physiological outputs according to this axis of polarisation. Read more

China Scholarship Council: Investigating the role of TET2 in the epitranscriptome of blood cells

The epigenetic mark of DNA methylation is established by DNMT (DNA methyltransferase) enzymes and has been shown to correlate with transcriptional states and influence cell identity and tumorigenesis in mammalian cells. Read more

MRC DiMeN Doctoral Training Partnership: Role of non-coding RNA in ageing-dependent epigenetic changes in blood cancer

Cancer-associated changes in gene expression and genome stability are often attributed to variations in DNA methylation. This is particularly true for blood cancers such as Chronic Lymphocytic Leukemia (CLL) and Non-Hodgkin’s Lymphomas (NHL) with increasing incidence/rates in the elderly. Read more

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