Centre for Genomic Regulation (CRG) Featured PhD Programmes
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Molecular Biology PhD Research Projects

We have 911 Molecular Biology PhD Research Projects

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Biological & Medical Sciences

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We have 911 Molecular Biology PhD Research Projects

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Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Understanding the gene regulatory landscape of embryonic stem cells and cancer cells

Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity. Read more

Investigating amphibian tolerance to the skin fungal disease chytridiomycosis

*** ABOUT THE PROJECT ***. The Frog Research Team in eastern Australia (. https://www.frogresearch.com/). has a PhD opportunity available for a highly motivated applicant to study frog chytrid fungal disease (3 year PhD). Read more

Modulating the ubiquitin ligase activity of MDM2

p53 tumour suppressor protein becomes activated in response to various genotoxic stresses and induces a variety signalling programmess to restore cellular homeostasis. Read more

Developing machine learning algorithms for early detection of hepatocellular carcinoma

Primary liver cancer is the third leading cause of cancer-related death worldwide. The most common type of liver cancer is hepatocellular carcinoma (HCC), which develops in the background of liver diseases, such as cirrhosis. Read more

Dissecting tumour stroma heterogeneity in high grade serous ovarian cancer using cutting edge mass spectrometry proteomics approaches

The High grade serous (HGS) ovarian cancer is the deadliest gynaecological cancer due to the limited availability of targeted therapies against the cancer cells, because only few targetable recurrent mutations have been identified in these cells. Read more

Laboratory of Gene Regulation

Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation. Read more

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