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University of Bristol Molecular Biology PhD Projects

We have 9 University of Bristol Molecular Biology PhD Projects

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Showing 1 to 9 of 9
  Data mining for microbial adaptation to climate change - MScR in Global Environmental Challenges
  Dr G Barker
Application Deadline: 1 August 2019

Funding Type

PhD Type

About the Project. Microbes are key members of nutrient and energy cycles in all global ecosystems. Whole meta genome DNA sequencing is increasingly used to characterise microbial ecosystems and vast amounts of data are deposited in the public domain every year.
  Molecular mechanisms controlling cardiac fibroblast proliferation during cardiac fibrosis
  Dr M Bond
Applications accepted all year round

Funding Type

PhD Type

Applicants are invited for a new self-funded PhD studentship to study the molecular mechanisms of cardiac fibrosis. Myocardial fibrosis is a significant global health problem associated with nearly all forms of heart disease.
  Novel anti-inflammatory mechanisms of cyclic-AMP in vascular smooth muscle cells
  Dr M Bond
Applications accepted all year round

Funding Type

PhD Type

A self-funded PhD studentship is available at the University of Bristol to study novel anti-inflammatory mechanisms of cyclic-AMP in vascular disease.
  Actin-dependent mechanisms of chromosome segregation in mammalian eggs
  Dr B Mogessie
Applications accepted all year round

Funding Type

PhD Type

Every human life starts when an egg is fertilised by a sperm. Fertilisable eggs are produced from oocytes by a specialised form of cell division called meiosis (1).
  Adhesion Pathways in Extracellular Matrix Organisation
  Prof J Adams
Applications accepted all year round

Funding Type

PhD Type

The extracellular matrix (ECM) provides structural and mechanical support to tissues and modulates cell phenotype and behaviour in health and disease.
  Chromatin and maintenance of genome stability
  Dr A Chambers
Applications accepted all year round

Funding Type

PhD Type

Within eukaryotes, DNA is packaged into chromatin. The basic unit of chromatin is the nucleosome, formed by the wrapping of ~147 bp of DNA around an octamer of histones proteins.
  Effects of transcription on genome stability
  Prof N J Savery
Applications accepted all year round

Funding Type

PhD Type

Transcription-coupled DNA repair (TCR) pathways prioritise the repair of certain lesions in "active" genes. These pathways help maintain genome integrity throughout the lifetime of multi-cellular organisms, and thus help prevent the occurrence of mutation that might cause cancer or other disorders.
  Elucidating the mechanism of SMC complexes
  Prof M Dillingham
Applications accepted all year round

Funding Type

PhD Type

The segregation of bacterial chromosomes is orchestrated by the co-ordinated actions of ParB and condensin [1]. ParB (also called Spo0J) is a site-specific DNA binding protein that binds at and around parS sequences near the origin of replication to form “ParB networks” which define the bacterial centromere [2].
  Microsoft Research 4-Year Studentship - Exploring motif-based design patterns for biological computation
  Dr T Gorochowski, Dr L Marucci
Application Deadline: 31 August 2019

Funding Type

PhD Type

In computer software engineering, design patterns provide reusable solutions to frequently encountered problems that are independent of the programming language used for implementation.
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