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Neuroscience / Neurology (self) PhD Research Projects

We have 122 Neuroscience / Neurology (self) PhD Research Projects

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We have 122 Neuroscience / Neurology (self) PhD Research Projects

Self-organisation as a theory of brain development

Self-organisation is a general theory of how function is assigned to cortical microcircuits. The theory predicts that a balance between cooperative and competitive interactions in local cortical circuits, consolidated by Hebbian learning, results in similar inputs being represented by nearby neurons. Read more

Perceptual stability in Virtual Reality across the adult lifespan

When we move, stationary parts of the world around us move on the retina. Of course, usually we correctly interpret this retinal motion as due to our own movement and not movement of the surrounding environment. Read more

Self-funded BMS project: Neuronal Src kinases: oncogenes in brain development?

The challenges of the developing human brain include co-ordinating the birth and migration of 100 billion neurons and the formation of their 1000 trillion synaptic connections. Read more

Self-funded BMS project: Ion channel signalling in cancer cells

Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing. Read more

Self-funded BMS project: Dissecting the mechanisms underlying sleep disturbances in Parkinson’s Disease

Ageing and neurodegenerative disorders, such as Parkinson’s, are characterized by a progressive loss of neurons in particular brain regions leading to characteristic behavioural changes including cognitive decline and sleep disruption. Read more

SELF-FUNDING MSc BY RESEARCH PROJECT: Cellular mechanisms underlying acetylcholine roles in cerebellar dependent behaviours.

The cerebellum is the largest sensorimotor structure in the brain and is crucial for motor coordination and learning. Little is known about how acetylcholine modulates cerebellar circuitry, and until our current work nothing was known about the role of cerebellar acetylcholine receptors in behaviour. Read more

SELF-FUNDING MSc BY RESEARCH PROJECT: Circadian Oscillators in Drinking and Feeding Brain Circuits.

Daily or circadian rhythms pervade all aspects of our physiology and behaviour (Hastings et al., 2018). By convention, these rhythms are attributed to the activity of the brain’s suprachiasmatic nuclei (SCN). Read more

Cancer: 3D model of the brain tumour perivascular niche: developing new approaches to target brain tumours

Aggressive brain tumours have dismal outcomes. Patients with glioblastoma multiforme, or brain metastases arising from tumours in other part of the body such as melanoma and breast cancer, have a median survival of only 14 months when treated with surgery followed by radiation and chemotherapy. Read more

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