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Neuroscience / Neurology PhD Research Projects

We have 365 Neuroscience / Neurology PhD Research Projects

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We have 365 Neuroscience / Neurology PhD Research Projects

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EASTBIO How does a mammalian cell physically organise the complex processes of gene expression and regulation?

  Research Group: Biomedical Sciences Research Centre
BACKGROUND. Accurate gene expression and regulation in mammalian cells is a hugely complex process, essential for cellular and organismal homeostasis. Read more

EASTBIO An integrated approach to deciphering the role of proline in intrinsically disordered protein regions

Proteins often have a well-defined structure that is key to it performing their function. Intrinsically disordered regions (IDRs) have no defined 3D structure and are found in many proteins, yet their purpose is poorly understood. Read more

Development of novel biotechnologies for scientific and medical applications

Talented and motivated students passionate about doing research are invited to apply for this PhD position. The successful applicant will join the Crick PhD Programme in September 2022 and will register for their PhD at one of the Crick partner universities (Imperial College London, King’s College London or UCL). Read more

Role of Arp2/3 complex isoforms in mouse development and tissue homeostasis

Talented and motivated students passionate about doing research are invited to apply for this PhD position. The successful applicant will join the Crick PhD Programme in September 2022 and will register for their PhD at one of the Crick partner universities (Imperial College London, King’s College London or UCL). Read more

(BBSRC DTP) Dynamics of neurogenesis during spinal cord regeneration

About 1200 people a year are left paralysed in the UK due to a Spinal Cord Injury (or SCI). This is because injuries involving the central nervous system (CNS) have poor capacity to repair or regenerate, thus resulting in a permanent loss of function. Read more

(BBSRC DTP) Defining the roles of mRNA methylation in circadian physiology and inflammation

Methylation is a pervasive biochemical modification targeting virtually all types of molecules in our cells. A key metabolic pathway called the “methyl cycle” synthesises S-adenosylmethionine (SAM), the methyl donor co-substrate used by over 200 substrate-specific methyltransferases described so far in humans. Read more

(MRC DTP) Unravelling the role of microglial interleukin-1alpha on neuronal activity and functions during cerebrovascular inflammation after stroke

Interleukin-1 (IL-1) drives inflammation after stroke, contributing to brain damage and poorer outcome. Blocking IL-1 actions with the IL-1 receptor antagonist (IL-1Ra) is beneficial in pre-clinical stroke models, and studies in stroke patients show that IL-1Ra is safe and may improve clinical outcomes. Read more

(BBSRC DTP) Remembrance of things past: Understanding the role of the environment in shaping microglia development

The ability to think, feel and create relies on the precise regulation of cortical circuit assembly during brain development. Circuits formed during development are reflections of the complex interplay between genetic and environmental factors. Read more

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