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Ophthalmology PhD Research Projects

We have 16 Ophthalmology PhD Research Projects

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We have 16 Ophthalmology PhD Research Projects

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Characterisation and treatment of patient iPSC-derived retinal organoids as an in vitro model of inherited retinal disease

Commercial partner: . Newcells Biotech Ltd. , Newcastle upon Tyne. Induced pluripotent stem cell (iPSC) derived 3D retinal organoids (ROs) mimic the architecture of the mammalian retina and can therefore be used as a physiologically relevant in vitro model. Read more

Exploring novel experimental therapeutics for mitochondrial disorders of the eye

Background. Primary mitochondrial genetic disease manifestations can involve almost all aspects of the eye. Mitochondrial disorders of the eye are often devastating genetic diseases, causing significant childhood and young adult blindness in the developed world. Read more

Three-dimensional structural mapping of the retinal neurovascular unit and the influence of diabetes

The aim of this PhD project is to better understand why people with diabetes are at risk of losing their vision. Diabetic retinopathy is a leading cause of visual impairment and blindness in developed countries. Read more

Bioengineering a full thickness cornea

Corneal blindness is the 4th leading cause of global blindness (WHO). Corneal scarring can be caused by trauma or infection and corneal replacement with donor corneas or synthetic (plastic) alternatives is currently the sole treatment to restore vision. Read more

Application of animal corneal cells for skin regeneration, tissue engineering and wound healing enhancement

  Research Group: Centre for Skin Sciences
Engineering of biological skin substitutes has progressed over the years from individual applications of skin cells, or biopolymer scaffolds, to combinations of cells and scaffolds for treatment, healing, and closure of acute and chronic skin wounds. Read more

Enhanced variant interpretation for the discovery of mechanisms underpinning Ophthalmic genomic disorders

This project will utilize large genomic sequencing datasets from the 100,000 genomes project and the UK BioBank to understand how genomic variation impacts the development and function of cells vital for correct vision. Read more

PhD position offered within EU Marie Sklodowska-Curie Initial Training Network EYE: European Young Eye

Short description of project. EYE is a project funded under H2020-ITN-2020 call (industrial doctorate modality). EYE will provide training and professional development in Vision Sciences and Optical Imaging Technologies to 5 Early Stage Researchers (ESR). Read more

The circadian clock as a regulator of information processing

Endogenous biological clocks are a ubiquitous feature of living organisms, driving rhythms in countless cellular and physiological functions, and influencing almost all biological processes. Read more

Designing an Internet-based intervention for carers and adults with acquired visual loss

  Research Group: Vision and Hearing Sciences Research Group
Research Group. Vision and Hearing Sciences Research Group. Proposed supervisory team. Prof Peter Allen. Dr Eldre Beukes. Prof Gerhard Andersson (External). Read more

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