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We have 15 Organic Chemistry (complex systems) PhD Research Projects PhD Projects, Programmes & Scholarships

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Organic Chemistry (complex systems) PhD Research Projects PhD Projects, Programmes & Scholarships

We have 15 Organic Chemistry (complex systems) PhD Research Projects PhD Projects, Programmes & Scholarships

Taking Light Induced Electron Paramagnetic Resonance In Cell for Biological Structural Determination

Studying the structure of proteins and other biological systems is an important step in understanding their function. Most structural studies are conducted in environments that are far away from native conditions, such as those found inside a cell. Read more

Reaction Monitoring and Structural Characterisation of Coordination Driven Self-Assembled Systems by Ion Mobility-Mass Spectrometry

Can you envisage a world where building a new catalyst or an artificial enzyme is like following an architectural plan for building a house? This is difficult as we don't even fully understand the construction materials! We research the properties of molecular building-blocks and their "constructed" aggregates, towards drawing up these type of blueprints. Read more

Healable Polymer Materials

The past four decades of science have witnessed how chemists have learnt from nature, in part by trial and error as well as elegant design, to understand and master the use of weak non-covalent interactions and self-assembly processes in synthetic systems to realise complex multi-component assemblies that exhibit attractive functionalities. Read more

Dynamic Nonequilibrium Compartmentalisation: Harnessing Transmembrane Gradients

Project. Nonequilibrium transmembrane processes are crucial in almost every biological process. Pumping and harnessing transmembrane gradients provides a convenient and efficient way for life to store and transduce energy. Read more

PhD in Supramolecular Chemistry: Metallo-Peptide Cages - Peptides as Adaptable Building Blocks in Metal-Organic Supramolecular Self-Assembly

We are a synthetic chemistry group working in supramolecular and biological chemistry, and nanotechnology. We work in the Francis Crick Institute in London, and at King's College London - find more details at https://www.mcternanresearchgroup.com/. Read more

Deploying safer robot chemists in real laboratory environments

Robotic chemists [1] are a totally new and disruptive development in human-centric labs, and these systems are already beginning to carry out complex experiments that require skills beyond sample transportation (e.g., sample weighing [2] and scraping samples from vials [3]. Read more

A new twist on catalysis: folded oligomers with organometallic termini

A key feature of biological systems is the storage and transmission of information across multi-nanometre distances, which maintains the complex chemical networks and functions within cells. Read more

Self-Immolative Polymeric Sensors

Stimuli-responsive compounds, such as self-immolative molecules and polymers,[1] have become significant targets in organic-based material development as systems of this type offer enormous potential in a diverse range of applications that span drug delivery, biological and chemical sensors, diagnostics, and degradable polymers or degrade-on-demand adhesives. Read more

Mechanochemistry with mechanical bonds

Any force developed at the macroscopic scale can induce dramatic changes at the molecular scale, even breaking covalent bonds.[1] Indeed, mechanical force is a formidable source of energy that, with its ability to distort, bend and stretch chemical bonds, is unique in its ability to promote reaction pathways that are otherwise inaccessible to traditional methods of activation. Read more

MSc by Research: Glueing proteins together with small molecules

Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more

Chemical modification of proteins via metal-mediated processes

Chemically modified proteins can be used to understand, treat, and diagnose disease. However, relatively few chemical reactions can be used to modify proteins, severely limiting the diversity and applications of new technologies. Read more

Understanding gene regulation by HDAC1 complexes in development and cancer

Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more
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