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Parasitology (self) PhD Research Projects

We have 12 Parasitology (self) PhD Research Projects

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We have 12 Parasitology (self) PhD Research Projects

Self-funded BMS project: Regulation of Leishmania cellular remodelling during life cycle transition

This project aims to investigate the signalling pathways that regulate key events in the life cycle of Leishmania and which protein kinases are essential and therefore potentially responsive to chemotherapeutic modulation. Read more

Self-funded BMS project: Helminth-induced changes to host haematopoiesis – a permanent problem?

More than a quarter of the global population is infected with a parasitic worm that causes a range of diseases. On-going work in our laboratories is focused on understanding how parasites such as schistosomes cause wide-ranging changes to host bone marrow and re-programme mammalian haematopoiesis. Read more

Novel anti-pathogen regulatory mechanisms driven by Human Guanylate Binding Proteins

Human GBPs are a family of seven ~65kDa GTPases whose expression is upregulated by IFNg, for example during an infection. All mammalian GBPs contain a GTPase domain and a C-terminal helical region. Read more

Host-Parasite Interactions

Our lab (. https://www.researchgate.net/profile/Jo_Cable). investigates host-parasite dynamics and the ecosystem impacts of invasive species. Read more

Genome-wide translational responses to stress

We are interested in gene regulation in responses to stress, using both simple model organisms, human and plant pathogens. Cells respond to stress conditions by launching complex programs of gene expression, both transcriptional and posttranscriptional, and which are often closely linked with each other. Read more

Ultrastructural analysis of the mouse whipworm as a model for human trichuriasis

Gastrointestinal dwelling nematode parasites are extremely successful parasites of both man and animals infecting over a billion people worldwide and are responsible for considerable morbidity and ill health worldwide. Read more
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