Pathology PhD Research Projects PhD Projects, Programmes & Scholarships

We have 102 Pathology PhD Research Projects PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The University of Manchester Faculty of Biology, Medicine and Health

The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more

Supervisors: Dr MM Mennon, Prof MH Buch

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Health and education outcomes of children with Sickle Cell Disease in England

Great Ormond Street Hospital for Children NHS Trust GOSH BRC Applied Child Health Informatics Theme (Non-Clinical) PhD Studentships

SCD is a serious, life-long condition that can cause anaemia, increased infection risk, and pain.1 Around 300 babies are born with SCD annually in the UK. Read more

Supervisors: Dr R Knowles, Prof P Hardelid

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Systemic infections accelerate tau spreading by promoting glial activation

University of Southampton School of Biological Sciences

Alzheimer’s disease (AD) is a neurodegenerative disease, with a complex biology. In this PhD project, we aim to explore the cellular and molecular mechanisms underlying tau pathology. Read more

Supervisor: Prof J Teeling

17 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute

Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more

Supervisors: Dr M Secrier, Dr L Cottone

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigating mechanisms of extra-cellular matrix remodelling and fibrosis in the gastrointestinal tract

University of Dundee School of Medicine

Inflammatory bowel diseases, such as Crohn's disease, are increasing in prevalence globally. These are caused by chronic inflammation in the gut, there is no cure and medications are not effective for all. Read more

Supervisor: Dr M Mclean

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Mechanism, cellular consequences and pharmacological manipulation of Ras palmitoylation for the treatment of cancer

University of Dundee School of Medicine

In humans, the genes HRAS, NRAS and KRAS encode three closely related proteins frequently mutated in cancer promoting unregulated cell growth. Read more

Supervisors: Dr N Fraser, Dr G Masson

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Leveraging novel automated diagnostic pathways with augmented precision medicine approaches for the early detection and risk stratification of liver disease

University of Dundee School of Medicine

Liver disease represents one of the fastest-growing causes of morbidity and mortality in the world. The principle aetiological variants are contained within the new nomenclature of steatotic liver disease (SLD). Read more

Supervisors: Dr P Brennan, Prof J F Dillon, Dr M Al-Khairalla

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Advancing Mass Spectrometry Tools for Endotyping Chronic Respiratory Diseases

University of Dundee School of Medicine

Chronic respiratory diseases, including COPD, asthma, and bronchiectasis, pose significant challenges in management due to their diverse clinical manifestations. Read more

Supervisors: Dr J Huang, Prof J Chalmers

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Exploring cardio-renal-metabolic interactions in patients with heart failure

University of Dundee School of Medicine

Recent years have highlighted the connections and shared pathophysiology between heart failure, renal impairment, diabetes and obesity, particularly with the evidence of benefit in all of these areas with SGLT2 inhibitors and GLP1-receptor agonists. Read more

Supervisor: Dr I Mordi

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigation of short-term effects of colchicine on blood proteins using proteomics

University of Dundee School of Medicine

The anti-inflammatory medication colchicine has been shown to significantly improve cardiovascular outcomes post heart attack and in chronic heart disease patient groups, suggesting it may be a suitable candidate for repurposing in cardiovascular diseases. Read more

Supervisors: Prof G Rena, Dr I Mordi, Prof C Lang

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Lessening Health Inequalities in Type 2 Diabetes Through Innovative Drug Repurposing

University of Dundee School of Medicine

Most older type 2 diabetes (T2D) drugs were developed through pre-clinical studies and then trials that model T2D as it is experienced by older white people (1). Read more

Supervisor: Prof G Rena

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Development of new molecular therapies to treat motor neuron disease (MND)

Macquarie University Centre for MND Research

The battle against Motor Neuron Disease (MND) is entering an exciting phase with the development of gene therapies aimed at reducing pathogenic proteins. Read more

Supervisors: Assoc Prof AL Lee, Assoc Prof MM Morsch

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Learning and Memory in the response to recurrent hypoglycaemia in diabetes

University of Dundee School of Medicine

Recurrent hypoglycaemia has both acute and chronic consequences and is greatly feared by people with type 1 diabetes. Work from our laboratory over the last few years has revealed that the brain adaptation to recurrent hypoglycaemia in type 1 diabetes represents a specialised form of memory called habituation. Read more

Supervisors: Prof R McCrimmon, Dr A McNeilly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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The inflammatory response to recurrent hypoglycaemia in diabetes

University of Dundee School of Medicine

Recurrent hypoglycaemia has both acute and chronic consequences and is greatly feared by people with type 1 diabetes. Read more

Supervisor: Prof R McCrimmon

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Vascularisation of tumour organoids for mechanistic and drug development

University of Dundee School of Medicine

Gliomas such as are the most common form of brain tumour, a subset Glioblastoma (GBM) are devastating adult brain cancer with high rates of recurrence and treatment resistance. Read more

Supervisors: Dr C Murdoch, Dr S Banerjee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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We have 102 Pathology PhD Research Projects PhD Projects, Programmes & Scholarships

Pathology PhD Research Projects PhD Projects, Programmes & Scholarships

We have 102 Pathology PhD Research Projects PhD Projects, Programmes & Scholarships

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