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Pathology PhD Research Projects

We have 70 Pathology PhD Research Projects

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We have 70 Pathology PhD Research Projects

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Understanding the heterogeneity of pathology in dementia with Lewy bodies to aid the interpretation of biomarkers

The primary pathology of dementia with Lewy bodies (DLB) is alpha-synuclein, however multiple studies have demonstrated that Alzheimer’s disease (AD) related pathologies (tau and beta amyloid) play an important role in disease progression driving spread of pathology and accelerating cognitive decline. Read more

Understanding Essential Tremor as a Miscalibrated Internal Model

Essential tremor (ET) is the most common reason for referral to a neurologist, with a prevalence of around 1-3%. Sufferers experience involuntary shaking of the limbs at around 5Hz; mild cases cause only social embarrassment, but more severe tremor can be disabling and limit activities of daily living. Read more

Novel tools for analysis of high-dimensional cytometry data - implications for cancer immunology and immunotherapy

The Systems Immunity Research Institute at Cardiff University is delighted to offer a full-time PhD studentship in Bioinformatics / Computational Biology funded by the Cardiff Cancer Research Hub for 3 years, starting on 1 April, 1 July or 1 October 2023 depending on the candidate's preference and availability. Read more

Selective drug uptake by cell surface transporters

Cell surface transporters and not diffusion is responsible for the transfer of metabolites across a cell’s membrane. Many types of drugs are structurally very similar to natural metabolites and as a consequence they are treated by the cell as though they are the natural homologue. Read more

Investigating the role of bioactive lipids in skin health

Human skin depends on systemic provision of fatty acids that are important to maintain the integrity of the epidermal barrier as well as to support the associated immune and inflammatory reactions. Read more

Characterization of the protective and therapeutic role of photobiomodulation on 3D oral mucosal and salivary gland models subjected to radiotherapy

Radiotherapy (RT) is a common standard therapy used for locally advanced head and neck malignant tumours. The radiation triggers the production of free radicals that can cause direct damage to the DNA structure of malignant cells. Read more

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