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Pharmacology PhD Research Projects

We have 69 Pharmacology PhD Research Projects

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We have 69 Pharmacology PhD Research Projects

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Understanding the Role of Extracellular Vesicle/Exosome Transport in the Visual System

For informal enquiries, please contact the supervisor. Dr Ben Mead (. MeadB@Cardiff.ac.uk. ). Cellular communication has typically been understood as cells secreting messenger proteins, known as cytokines and growth factors, which bind to receptors on recipient cells and elicit their desired effect. Read more

EPSRC DTP PhD project: Artificial intelligence enabled iDEntification of potential immune biomarkers in COgnitive DEcline (DECODE)

The University of Bath is inviting applications for the following PhD project commencing in October 2023. Eligible applicants will be considered for a fully-funded studentship – for more information, see the Funding Notes section below. Read more

The utilisation of cell-membrane wrapped nanoparticles as a novel CNS drug delivery system

  Research Group: Biomedical Sciences
Cell membrane-wrapped nanoparticles (NP) are under investigation in multiple applications from vaccines to drug delivery systems due to their prolonged circulation time, reduced uptake by the mononuclear phago-cyte system, as well as tissue- and inflammation-targeting properties. Read more

Novel new drug delivery systems for ocular delivery

  Research Group: Biomedical Sciences
Intravitreal Injections (IVIs) are extremely effective for drug delivery, they can deliver large amounts of drug directly into the eye with minimal effect of the medications elsewhere in the body. Read more

Anticancer Activity of Rhamnolipids and Sophorolipids Biosurfactant Congeners

  Research Group: Biomedical Sciences
Rhamnolipids and sophorolipids are glycolipidic biosurfactants produced by bacterial and yeast cells, respectively and possess both hydrophobic and hydrophilic moieties. Read more

Treating bacterial infections using aldehydes

Mycobacteria is a large class of bacteria that includes a number of infamous human pathogens, including Mycobacterium tuberculosis (Mtb) and Mycobacterium leprae, the agents of tuberculosis (TB) and leprosy respectively. Read more

A synthetic biology approach to dissect the post-anaphase functions of mitotic kinases

  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
Cell division is essential for life. The complex mechanochemical processes of chromosome segregation and cytokinesis are coordinated by the group of multifunctional protein kinases (mitotic kinases) such as Aurora kinases and Polo kinases under the master regulation of the cyclin-dependent kinases. Read more

Understanding mechanical induced signalling in the healthy tendon

Tendon problems are a common medical complaint, our current understanding highlights that mechanical stimulus (running and walking) triggers adaptations at the cellular level1. Read more

Towards new drugs and diagnostics for tuberculosis: Elucidating and exploiting essential pathways in the Mycobacterium tuberculosis pathogen

  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
Tuberculosis (TB) is a major global health challenge. TB is the leading cause of death worldwide from a single bacterial pathogen killing more people than HIV and malaria combined. Read more
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EASTBIO Prediction of protein-ligand binding via machine learning methods to accelerate medicine discovery

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Predicting which compounds will bind to a drug target (such as an enzyme) and which will not is a challenging problem. Read more

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