We have 62 University of Edinburgh, School of Biological Sciences PhD Research Projects PhD Projects, Programmes & Scholarships
University of Edinburgh, School of Biological Sciences PhD Research Projects PhD Projects, Programmes & Scholarships
We have 62 University of Edinburgh, School of Biological Sciences PhD Research Projects PhD Projects, Programmes & Scholarships
Last chance to apply
EastBio: Whole genome duplication and the polyploidy continuum.
Research Group:
Institute of Ecology & Evolution
Polyploidy—whole genome duplication—is a major mutation that leads to a doubling of the chromosome number. This process has attracted the interest of biologists for over a century because of its critical role in generating diversity, influencing genes, species, and communities. Read more
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EastBio: What makes a super-spreader? Unravelling the genetics of host infectiousness.
Research Group:
Institute of Ecology & Evolution
Individuals are known to vary extensively in their genetic resistance to infectious pathogens. Over the last decades a plethora of genetic studies have unraveled the genetic architecture and identified key genetic loci or genes associated with disease resistance in humans and animals. Read more
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EastBio: Understanding selfish genes and selfish self-fertilisation.
Research Group:
Institute of Ecology & Evolution
Toxin-antidote (TA) gene pairs are a form of selfish genes that ensure their transmission by causing host lethality if not inherited together. Read more
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EastBio: Understanding immune protein complex assembly in plant cells
Research Group:
Institute of Molecular Plant Sciences
How plants detect pathogen and confer disease resistance is crucial to protect crop yield from biotic stress. In plants, intracellular immune receptors can detect specific pathogenic proteins secreted into the host cell, and this detection is crucial to trigger immune activation and subsequent disease resistance. Read more
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EastBio: Understanding how chromatin controls antigenic variation in Trypanosoma brucei
Research Group:
Institute of Cell Biology
Trypanosoma brucei is the etiological agent of trypanosomiasis in humans and animals and remains a significant, neglected tropical disease. Read more
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EastBio: The role of epigenetic regulation in red blood cell development
Research Group:
Institute of Cell Biology
Red blood cell differentiation (erythropoiesis) is an exquisitely orchestrated process that progressively promotes commitment and differentiation of hematopoietic stem cells, to generate highly specialized erythrocytes needed for oxygen transport. Read more
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EastBio: The mitotic tsunami: how cells re-build their identity in G1.
Research Group:
Institute of Cell Biology
The Buonomo and Gilbert groups aim at building an understanding of the eukaryotic nuclear function that integrates knowledge from what are traditionally viewed as different fields, such as epigenetics, DNA replication and nuclear architecture. Read more
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EastBio: The genetics of ageing in a wild mammal.
Research Group:
Institute of Ecology & Evolution
Ageing, the deterioration in physiological function during adulthood, is responsible for late-onset disease and mortality in human, captive and wild animal populations. Read more
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EastBio: The effects of circadian rhythms in potassium concentration on cell biology.
Research Group:
Institute of Molecular Plant Sciences
Circadian rhythms are a fundamental feature of life, found in all eukaryotes. In our own bodies, plants, and fungi, every cell keeps time by itself. Read more
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EastBio: Targeting proteotoxic stress and aneuploidy in Crytococcus neoformans
Research Group:
Institute of Cell Biology
Cryptococcus neoformans is an important human fungal pathogen with a fascinating life cycle, forming polyploid titan cells during infection in a bid to evade the immune system. Read more
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EastBio: Specificity and function of RNA communication in gastrointestinal nematode-host interactions.
Research Group:
Institute of Immunology & Infection Research
Research in the last decade has demonstrated that ribonucleic acids (RNA) can transmit information between cells and that parasites exploit this communication pathway to alter the host environment and increase parasite survival. Read more
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EastBio: Spatial regulation of mRNAs in filamentous fungi
Research Group:
Institute of Cell Biology
Filamentous fungi are critical for global nutrient cycling, and many filamentous fungi are important pathogens of plant crops, animals, and humans, affecting food security and economy, and animal and human health. Read more
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EastBio: Social behaviour, health and ageing in a wild vertebrate population
Research Group:
Institute of Ecology & Evolution
Social connectedness is fundamentally important to human health and there is a widening appreciation that sociality may underpin variation in animal health in both livestock and in the wild. Read more