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Structural Biology PhD Research Projects

We have 89 Structural Biology PhD Research Projects

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We have 89 Structural Biology PhD Research Projects

21_15 Targeting the sphingolipid biosynthesis pathway of protozoan parasites as drug targets

Further Information. The start date for this 4 year funded project is October 2021 as part of Cohort 3 of EPSRC Centre for Doctoral Training (CDT) in Molecular Sciences for Medicine (MoSMed). Read more

IMAGinG: Regulatory interactions of Ikaros family transcription factors with active and repressive nuclear compartments

  Research Group: Lymphocyte Development
Background and Aims. The Ikaros family of sequence-specific DNA binding proteins is central to haematopoiesis, and the founding member IKZF1 is recurrently mutated in human progenitor B cell acute lymphoblastoid leukaemia 1 (B-ALL). Read more

PhD Positions in Chemical Biology and Drug Development

Post-doc Position in Chemical Biology.  A project of our laboratory, enabled by an ERC Advanced Grant, aims at developing macrocycle-based therapeutics for currently "untargetable" protein targets (. Read more

PhD studentship in Molecular Biosciences - Deciphering a mitoribosome quality control machinery

Number of awards. 1. Start date and duration. 20th September 2021 for 3 years. Overview. Our lab's research at the Wellcome Centre for Mitochondrial Research (WCMR), experimentally addresses fundamental questions in molecular and cell biology of mitochondria and their integration in the cell. Read more

New carbohydrate-active enzymes for improved detergent sustainability (Ref: RDFC21/HLS/APP/BLACKP&G)

Introduction – Many detergent formulations are currently formulated with carbohydrate-active enzymes (CAZymes) designed to improve cleaning by targeting a variety of polysaccharide-based soil components. Read more

Modelling blood motion in deformable vessels

This project aims to introduce a novel approach in studying blood flow in deformable vessels by simultaneously considering both the fluid (blood) and the structure (vessel) through analytical and numerical approaches. Read more

Molecular mechanisms underlying Parkinson's disease

There is great need for improved understanding of the mechanistic biology underlying Parkinson’s disease. Such knowledge will help with development of new drugs that slow or even halt the progression of the disease. Read more

Regulation and mechanics in polarity

Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more

Analysing the conformations of the ATPase p97 using cryo-Electron Microscopy

The AAA ATPase p97 is a molecular machine that converts energy stored in ATP into conformational changes to segregate proteins in a variety of essential cellular processes, ranging from protein degradation, gene transcription and membrane fusion. Read more

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