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Structural Biology PhD Research Projects

We have 167 Structural Biology PhD Research Projects

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We have 167 Structural Biology PhD Research Projects

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Pancoronavirus neutralizing antibodies

Talented and motivated students passionate about doing research are invited to apply for this PhD position. The successful applicant will join the Crick PhD Programme in September 2022 and will register for their PhD at one of the Crick partner universities (King’s College London). Read more

(BBSRC DTP) The evolution of odorant receptors in the domestication of Aedes mosquitoes: the link to zoonotic disease emergence

Manmade environmental change has triggered adaptation to domestic habitats in several pest species, including mosquitoes. As well as being of fundamental biological interest, the evolutionary process of domestication also results in the transmission of formerly zoonotic diseases of wildlife to livestock and humans. Read more

(BBSRC DTP) Mechanism of early steps in protein synthesis by cryoEM imaging of supramolecular complexes

The aim of this project is to understand the mechanism and control of protein synthesis in eukaryotic cells at the molecular level, particularly focused around the role of the eukaryotic translation initiation factors eIF2, eIF5 and eIF2B [1,2]. Read more

Understanding the function and functional mechanism of mitochondrial AAA proteinases

The mitochondrion is a vitally important organelle of eukaryotic cells. Mitochondrial AAA proteinases play important roles in mitochondrial function and protein homeostasis (proteostasis) by removal of unwanted proteins and regulating the function of mitochondrial proteins. Read more

Understanding human sulfatases involved in heparan sulfate degradation

  Research Group: Biomedical Sciences Research Centre
Various types of carbohydrates, or sugars, are ubiquitous throughout nature and perform a number of important functions in our cells. Read more

Using spider venoms to develop novel, safer, insecticides for crop protection

For protecting crops, neonicotinoids have become the most widely used class of insecticides in the world. However, their use has been restricted in the European Union amidst fears that they are having adverse effects on pollinators such as the honey bee, Apis mellifera. Read more

EASTBIO - Structural and biological characterisation of a novel virulence mechanism in Gram-negative pathogens

Gram-negative pathogens are responsible for major disease problems in humans and animals, and a better understanding of the mechanisms for how these bacteria cause infections is key to identify more effective ways to prevent and treat outbreaks. Read more

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