Imperial College London Featured PhD Programmes
Imperial College London Featured PhD Programmes
Life Science Zurich Graduate School Featured PhD Programmes

Structural Biology PhD Research Projects

We have 150 Structural Biology PhD Research Projects

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We have 150 Structural Biology PhD Research Projects

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Understanding and controlling β-strand mediated PPIs using bespoke chemical modifications

  Research Group: School of Chemistry
Chemical probes are advantageous in studying the molecular mechanisms of health and disease; they uniquely allow temporary and titratable modulation of a target protein’s function, permitting evaluation of its functional role. Read more

Using Dynamic Combinatorial Selection Methods to Identify Chemical Modifications of Protein Function

  Research Group: School of Chemistry
This PhD studentship will exploit chemical biology approaches to understand and manipulate the aggregation behaviour of α-synuclein, an intrinsically disordered protein which plays a key role in the neurodegenerative condition. Read more

Understanding the role of alpha-actinin in cardiac disease: from molecules to in vivo models

In the heart and skeletal muscle, the Z-disc is a crucial structure to anchor thin filaments of the contractile units. Moreover, the Z-disc is recognised as a signalling hub, sensing and responding to changes in the environment. Read more

Biovalorisation of polyethylene plastic waste (Ref: MRDF22/HLS/BB/MUNOZ)

Plastic waste is omnipresent in the biosphere and has become an overwhelming environmental concern. Only a small fraction of plastics is recycled or processed when reaching their end of life. Read more

Using mass spectrometry to uncover microbiology's secrets

Mass spectrometry is becoming an increasingly important tool in microbiology. This advancing technology is rapidly being applied to push boundaries in our understanding of protein systems. Read more

MRC DiMeN Doctoral Training Partnership: Calmodulin signalling as a potential therapeutic target for COVID-19 infection

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has emerged in December 2019 in China as the newest member of a family of coronaviruses (CoV) and has rapidly spread worldwide. In approximately 20% of cases, SARS-CoV-2 can invade the respiratory system of humans and cause mild to severe respiratory disorders which have been named coronavirus disease 19 (COVID-19). Read more

PhD topic / position: Structure of Biosystems and Molecular Materials

Supervisor: Radek Marek. Topic 1. Designing modified DNA fragments. Annotation: The novel forms of nucleotide moieties will be incorporated in silico in oligomers with sequences relevant for biosystems. Read more

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