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Pharmacology / Toxicology PhD Projects in the UK

We have 122 Pharmacology / Toxicology PhD Projects in the UK

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Showing 1 to 10 of 122
  Can PTP1B inhibition rewire macrophage function to improve anti-tumour immunity in breast cancer treatment?
  Dr H M Wilson, Prof N Vargesson
Application Deadline: 28 June 2019

Funding Type

PhD Type

Treatment for breast cancer is improving but new therapies are often only successful in a proportion of patients and some patients develop resistance.
  Combining melatonin and omega-3 fatty acids to manage chemotherapy-induced peripheral neuropathy and spinal injury-induced neuropathic pain.
  Prof H Galley, Dr W Huang
Application Deadline: 28 June 2019

Funding Type

PhD Type

Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating complication during cancer treatment, which can lead to chemotherapy drug dose reduction or treatment cessation.
  Identifying novel thalidomide analogs that safely treat models of human disease and their molecular targets of action.
  Prof N Vargesson, Prof L Erskine
Application Deadline: 28 June 2019

Funding Type

PhD Type

Thalidomide is a notorious drug which was originally used as a sedative (between 1958-1962) but was also prescribed to pregnant women suffering from morning sickness.
  Multidisciplinary approach to understand how a pregnant woman’s lifestyle affects her child’s health.
  Prof P A Fowler, Dr S Bhattacharya
Application Deadline: 28 June 2019

Funding Type

PhD Type

The unborn baby is exposed to many environmental toxins in the mother’s womb and these can have lasting effects on their health in the future.
  Searching for the predictors of high blood pressure in women and their offspring - a bioinformatics approach.
  Dr G S Bewick, Dr S Bhattacharya, Dr E Collie-Duguid
Application Deadline: 28 June 2019

Funding Type

PhD Type

We are seeking to understand the causes of hypertension (high blood pressure). Hypertension is THE greatest preventable risk factor for premature death worldwide [1] through inducing cardiovascular disease, stroke, and kidney damage.
  Disrupting the regulatory mechanisms that allow hospital acquired infections to resist antibiotic therapy.
  Dr R McCarthy
Applications accepted all year round

Funding Type

PhD Type

The discovery of penicillin over 90 years ago and its subsequent uptake by healthcare systems around the world revolutionised global health and wellbeing.
  Inhibiting cell metabolism to enhance tumour cell death
  Dr C Bubici, Dr S Papa
Application Deadline: 31 January 2020

Funding Type

PhD Type

As you read this, millions of your cells from your body are dying. Do not panic – this is not bad news. Most of them are either superfluous or potentially harmful, so you are better off without them.
  Nanoparticles in drug delivery
  Dr G Stenbeck, Dr U Kishore
Applications accepted all year round

Funding Type

PhD Type

Nanoparticles (NPs) are materials with overall dimensions in the nano scale range (5nm-100nm). Due to their unique physicochemical properties, they have found a wide range of applications and are currently explored as drug and gene delivery vehicles.
  Telomere length elongation following treatment with chemotherapeutic drugs. Aim: To investigate the mechanisms which leads to telomere length elongation after treatment with tricostatin A and azacytidine.
  Dr T Roberts
Applications accepted all year round

Funding Type

PhD Type

Telomeres are specialised structures, which are present at the ends of chromosomes and serve to protect the chromosome from degradation during cell division.
  Discovering zinc signalling mechanisms to prevent breast cancer progression
  Dr K Taylor
Applications accepted all year round

Funding Type

PhD Type

Zinc is essential for all living cells, yet the true extent of its role is only now emerging and is fully suggestive of a complexity and importance of that attributed to calcium.
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