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University of Cambridge PhD Projects

We have 25 University of Cambridge PhD Projects

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  Alternative pre-mRNA splicing
  Prof C W J Smith
Applications accepted all year round

Funding Type

PhD Type

The following is a general statement about ongoing research on alternative splicing in the Smith lab. Specific projects will be available in one or more of these areas.
  Evolution and biochemistry of photosynthesis - electron transfer reactions, renewable energy production, biotechnology, and chloroplast genomes
  Prof C J Howe
Applications accepted all year round

Funding Type

PhD Type

The common theme of our work is the biochemistry and evolution of photosynthesis.
  Mechanism of transmembrane receptor activation
  Dr M Hyvonen
Applications accepted all year round

Funding Type

PhD Type

Applications are invited for a PhD position, starting in October 2019, in the group Dr Marko Hyvonen at University of Cambridge (http://hyvonen.bioc.cam.ac.uk/) to study the mechanism of transmembrane signalling by TGFbeta family growth factors.
  Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways.
  Prof N J Gay
Applications accepted all year round

Funding Type

PhD Type

This group participates in the Wellcome Trust 4 year PhD programme in Developmental biology., MRC and BBSRC Doctoral Training Programmes.
  Small G proteins and their effectors as therapeutic targets in cancer
  Dr D Owen
Applications accepted all year round

Funding Type

PhD Type

For the majority of cancers the acquisition of invasive and metastatic characteristics leads to incurable disease in the host.
  Structure, regulation and dynamics of small G proteins and their interactions with membranes and effector proteins
  Dr H Mott
Applications accepted all year round

Funding Type

PhD Type

Our lab are interested in cell signalling via small G proteins of the Ras superfamily. We use a range of biochemical, biophysical and structural approaches to understand these fascinating proteins, which are involved in multiple cellular processes and are often deregulated in diseases such as cancer.
  Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
  Prof E D Laue
Applications accepted all year round

Funding Type

PhD Type

The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells.
  Developing Synthetic Models of the Cochlea to Investigate Cochlear Implant Stimulation Spread
  Prof M Bance
Application Deadline: 3 December 2019

Funding Type

PhD Type

(PhD- suitable for engineering, materials, chemical engineering and biomedical backgrounds). (co-supervised by Professor George Malliaras, Dr Debi Vickers and Dr Bob Carlyon).
  Development and Application of Novel PET Markers of Neuroinflammation
  Dr F Aigbirhio
Application Deadline: 3 December 2019

Funding Type

PhD Type

This project’s objective is to develop novel in vivo PET probes for application as sensitive markers of neuroinflammatory processes which are key components of several pathologies, including stroke, traumatic brain injury, multiple sclerosis and dementias.
  Does Histone Deacetalyse Inhibition Reduce Atherosclerosis and Stroke Risk (PhD only) 
  Prof H Markus
Application Deadline: 3 December 2019

Funding Type

PhD Type

The Cambridge Stroke Group led the identification of the HDAC9 (histone deacetalyse 9) gene as a risk factor for stroke. The association is specific for large artery stroke due to atherosclerosis.
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