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University of Sheffield Featured PhD Programmes
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Virology PhD Research Projects

We have 48 Virology PhD Research Projects

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We have 48 Virology PhD Research Projects

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Developing a virus-like particle (VLP) Polio vaccine

Poliovirus is a non-enveloped RNA virus, spread via the faecal-oral route, that causes the disease Poliomyelitis (Polio). In most cases poliovirus infection causes mild symptoms but in a small proportion (. Read more

Understanding cellular receptors mediating signalling and viral infection - molecular mechanisms and development of new therapeutics

Cellular receptors initiate signalling pathways that regulate all aspects of cell behaviour and these receptors are key therapeutic targets for a wide range of diseases including cardiovascular disease and cancer. Read more

PhD Studentship: Exploiting viral ecology to combat problem organisms in biological wastewater treatment

Overview. In nature, viruses drive bacterial abundance, activity, and community composition. they are responsible for up to 100% of bacterial mortality every day, severely affecting ecosystem function. Read more

Coronavirus regulation of cellular antiviral responses and cross species transmission

Coronaviruses (CoV) can cross the species barrier to generate highly pathogenic viruses. Recently, SARS-CoV, MERS-CoV and SARS-CoV-2 emerged following jumps from bats, via an intermediate host into humans, while SADS-CoV jumped from bats into pigs. Read more

Coronavirus regulation of cellular antiviral responses and cross species transmission

Coronaviruses (CoV) can cross the species barrier to generate highly pathogenic viruses. Recently, SARS-CoV, MERS-CoV and SARS-CoV-2 emerged following jumps from bats, via an intermediate host into humans, while SADS-CoV jumped from bats into pigs. Read more
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Comparing the Airborne Survival of Enveloped and Non-enveloped Viruses

Applications are invited for a 4 year PhD studentship starting in Autumn 2022 as part of the. EPSRC CDT in Aerosol Science. Project description. Read more
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BBSRC PhD Studentship in Improved viral vector design for homologyindependent targeted integration (HITI) [Project 2022/08]

In collaboration with Oxford Biomedica. Gene therapies for recessive disorders are becoming commonplace, but treatments for dominant gain-offunction disorders are under-researched due to the need to achieve both knock down of the dominant mutant allele and replacement of normal function. Read more
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BBSRC PhD Studentship in Understanding the cellular and humoral immune response to viral vectors [Project 2022/06]

In collaboration with Oxford Biomedica. Viral vectors enable safe and efficient delivery of genes into target tissues and organs, which have transformed medicine, biomedical research and vaccine development. Read more
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Evaluating the effectiveness and cost-effectiveness of one-health vaccination strategies

Zoonotic viruses, which can be transmitted from animals to humans, pose a particular challenge for disease control. It is possible to use One Health approaches to controlling human infections by controlling such viruses in animal or human populations. Read more
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Establishing clinical diagnostic metagenomic sequencing methods to detect a wide range of pathogens and antimicrobial resistance genes.

Next generation sequencing methods have advanced significantly in recent years, with Oxford Nanopore Technology (ONT) platforms ideally placed for adoption into NHS laboratories due to suitability for rapid turnaround sequencing and low hardware footprint. Read more

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