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Physical Chemistry (structural biology) PhD Projects, Programs & Scholarships

We have 18 Physical Chemistry (structural biology) PhD Projects, Programs & Scholarships

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  Dynamic Structural Biology Studentship (stipend £2,000 above the standard UKRI rate)
  Prof E Raven, Dr A Orville, Prof P Moody
Application Deadline: 15 March 2020

Funding Type

PhD Type

Applications are invited for a studentship in dynamic structural biology starting in October 2020 to be jointly supervised by Dr Allen M.
  Establishing NMR chemical shifts as reliable reporters of atomic charge distributions in enzymes
  Prof J Waltho, Prof P Popelier
Applications accepted all year round

Funding Type

PhD Type

Enzymes are not only central to life but also to the growing need to harness elements of the natural world to the benefit of mankind.
  Molecular mechanisms of herpesviral infection
  Dr A Golovanov
Applications accepted all year round

Funding Type

PhD Type

Herpes viruses are known to cause a wide range of human diseases, ranging from simple cold sores to cancer, Kaposi Sarcoma. Kaposi Sarcoma, for example, is a type of cancer which affects immunocompromised patients and is endemic in Africa, where it is linked with the spread of HIV infection and AIDS.
  The chemistry and biophysics of phosphoryl transfer enzymes
  Prof J Waltho, Dr A Almond
Applications accepted all year round

Funding Type

PhD Type

One of the most remarkable features of the chemistry of living organisms is the evolutionary utilisation of phosphate esters to provide biopolymers that encode genetic information, deliver temporal protein regulation, generate and distribute free energy throughout the cell, and to provide a ubiquitous handle for metabolic intermediates.
  Development of metabolomics for understanding AMR in mixed infections
  Prof R Goodacre
Applications accepted all year round

Funding Type

PhD Type

Without correct antibiotic stewardship we could be cast back to a pre-infective era where we have run out of antibiotics to treat life-threatening infections.
  Understanding and dissecting microbial communities with Raman spectroscopy
  Prof R Goodacre
Applications accepted all year round

Funding Type

PhD Type

We have shown that it is possible to label bacteria with heavy isotopes of carbon (13C) and nitrogen (15N) and this incorporation within cellular biomass of heavy isotopes has led to significant shifts in certain vibrational modes from amino acids and nucleic acids that can be readily detected with Raman spectroscopy.
  Differential ion mobility spectrometry and mass spectrometry for proteomics
  Prof H J Cooper
Applications accepted all year round

Funding Type

PhD Type

Research in our laboratory focuses on the application of state-of-the-art mass spectrometry techniques to the global analysis of peptides and proteins.
  Cationic antimicrobial peptides as anticancer agents
  Dr R Green, Prof R A Frazier
Applications accepted all year round

Funding Type

PhD Type

Cationic peptides are widespread in nature where they play a key role in host defense within plants and animals. The mechanism by which these peptides interact with cell membranes potentially leads to these being less prone to antimicrobial resistance than conventional antibiotics.
  Characterising surface properties of protein biopharmaceutical molecules
  Dr A Golovanov, Dr J Warwicker
Applications accepted all year round

Funding Type

PhD Type

Protein biologicals have great potential for the effective treatment of a wide range of diseases. However, aggregation and instability are inherent issues with all protein pharmaceuticals, which is a problem that can limit their utility and developability.
  Development of pulmonary dosage forms for improved antibacterial activity
  Dr H Al-Obaidi
Applications accepted all year round

Funding Type

PhD Type

"Conventional formulations for drug delivery to the lungs are limited to less than a few milligrams as a fine particle fraction.
  Observing Nucleic Acid Aptamer Binding with Ultrafast 2D-IR Spectroscopy
  Prof N Hunt
Applications accepted all year round

Funding Type

PhD Type

The project will be a collaboration with Prof Glenn Burley (University of Strathclyde). Background. The strong and specific binding of small molecules and proteins to DNA has relevance across many areas, from fundamental biophysics, through chemical biology to nanotechnology.
  Atomistic Modelling Studies of New Materials for Lithium Batteries
  Prof M S Islam
Application Deadline: 1 March 2020

Funding Type

PhD Type

The University of Bath is inviting applications for a PhD opportunity in the Department of Chemistry under the supervision of Prof Saiful Islam.
  MRC DTP 4 Year PhD Programme: Bacterial stress sensing and antibiotic action
  Dr U Zachariae, Dr M Bergkessel
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Designing colloidal films and membranes with complex interactions
  Dr M Haw
Applications accepted all year round

Funding Type

PhD Type

Porous films and membranes are important for applications such as adsorbing, separating and storing gases, cleaning water and soils, sensor devices and many others.
  Understanding Movement and Mechanism in Molecuar Machines (MACMILLANF2U20SF)
  Dr F MacMillan
Application Deadline: 31 May 2020

Funding Type

PhD Type

We study the architecture and functional dynamics of membrane proteins, especially many medically relevant membrane transport systems.
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