Project outline: . The renin angiotensin system (RAS) is a hormonal cascade mediating cardiovascular function. The RAS is key to the development of cardiovascular diseases, including cardiac remodelling in hypertension and heart failure and atherosclerosis. Read more
Our ultimate purpose is to work in service of patients. RCSI was founded by Royal Charter on 11th February 1784, to set and support professional standards for surgical training and practice in Ireland. Read more
Blood vessels, running across all tissues, provide a unique biological hub that integrates ageing signals at the molecular, cellular, and organ levels. Read more
We have developed a novel system to measure tissue levels of hormones, metabolites and inflammatory mediators over the full 24 hours in people going about their normal everyday lives. Read more
Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more
Numerous studies have demonstrated the importance of B vitamins (e.g., B6, B12 and folate) for optimal physiological and neurological functioning. Read more
Loughborough University is a top-ten rated university in England for research intensity (REF, 2014) and an outstanding 66% of the work of Loughborough’s academic staff who were eligible to be submitted to the REF was judged as ‘world-leading’ or ‘internationally excellent’, compared to a national average figure of 43%. Read more
Loughborough University is a top-ten rated university in England for research intensity (REF, 2014) and an outstanding 66% of the work of Loughborough’s academic staff who were eligible to be submitted to the REF was judged as ‘world-leading’ or ‘internationally excellent’, compared to a national average figure of 43%. Read more
G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
Deficiencies of thyroid hormone are common throughout the globe. Adult-onset hypothyroidism is prevalent in around 8-10% of the population and is associated with reproductive disorders, anxiety, depression, and impairment of memory. Read more
*** ABOUT THE PROJECT ***. The Frog Research Team in eastern Australia (. https://www.frogresearch.com/). has a PhD opportunity available for a highly motivated applicant to study frog chytrid fungal disease (3 year PhD). Read more
Our laboratory is interested in how the brain regulates appetite and body weight. We use a multi-disciplined approach; studying gene expression, cellular function, brain connectivity and behaviour. Read more
Organ on a chip devices are an emerging technology which employ microfluidics to grow 3D tissues, mimicking the physiological conditions found in vivo. Read more
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