10 PhD Positions in Braunschweig (Germany)
"Protein Complex Assembly PROCOMPAS"
(m/f/d)
Start of funding: 1 October 2019
Funded for three years
The project
Protein complex dynamics orchestrate biochemical processes at all stages of life.
They are essential to control cellular metabolism, transport, regulation, structure and
mobility. Therefore, they are strictly regulated and require factors that ascertain the
temporal and spatial ordering of assemblies. Within the Research Program we will
study central principles of protein complex assembly systematically using two
representative model systems: (1) The eukaryotic molybdenum cofactor biosynthesis
complex, and (2) the bacterial electron transporting respirasome. Both types of
complexes are of essential importance for the organism and malfunction leads to
death. The elucidation of these processes will advance our understanding of e.g.
protein-protein interaction, ligand recognition, product-substrate channeling,
posttranslational modifications, up to the formation of supramolecular complexes and
their spatial positioning within the cell.
The program
The joint Graduate Program of the Technical University of Braunschweig and the
Helmholtz Center for Infection Research offers 10 PhD positions that are open for
dedicated doctoral researchers to explore protein complex assembly. A broad
methodological spectrum will be employed ranging from biochemical and molecular
methods, such as advanced cloning and enzyme purification, protein mutagenesis,
bioinformatics and systems biology, all kinds of mass spectrometry, diverse kinds of
advanced spectroscopy including single molecule spectroscopy, X-ray
crystallography, proteomics and live cell imaging.
The positions are in in the areas of molecular biochemistry, proteomics,
structural biology, bioimaging, advanced spectroscopy, catalysis and
biophotonic. Protein complex assembly will be studied in fungal, mammalian, plant
and/or bacterial cells.
You will join a passionate team of researchers led by experienced principal
investigators. Supported by a tailored teaching concept our doctoral researchers
progress towards independent scientists. There are no tuition fees. Salaries are
according to the German employment tariff (0.65% TV-L E13). International
cooperation is supported by an active guest scientist program. Stays abroad in
partner laboratories and the
participation in international symposia are part of the curriculum. We offer soft skill
courses and a mentoring program.
Requirements
We invite applications from talented and ambitious students preferably with a
background in protein studies and a vivid interest in interdisciplinary projects within the
field of protein complex assembly. Applicants should hold a Master’s degree (or
equivalent degree) in biological sciences, chemistry, physics, biochemistry, molecular
biology, biophysics, biotechnology, or a related discipline. Students of all nationalities
are encouraged to apply. The language of instruction is English, and applicants are
expected to be proficient in this language.
Candidates will be selected on a competitive basis and will be selected without regard
to sex, race or nationality.
Information and Application
Please send a CV (including the contact details of two or three references),
certificates/transcripts and a letter of motivation to Dr. Dagmar Zwerschke
(procompas@tu-braunschweig.de) with the subject title “PROCOMPAS PhD”.
For further questions, feel free to contact Dr. Dagmar Zwerschke
(procompas@tu-braunschweig.de).
For further information about the different projects and the program visit
www.tu-braunschweig.de/procompas
Applications deadline is 14th July 2019
Selected applicants will be invited for a job interview until 28th July. The interview
includes an oral presentation of the applicant's previous research and takes place in
Braunschweig or via Skype.