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3 PhD positions avaliable within the DFG-funded Clinical Research Unit PhenoTImE

3 PhD positions avaliable within the DFG-funded Clinical Research Unit PhenoTImE (CRU 337-2)

The University Hospital Essen offers first class medical services in the Ruhr metropolis. Every year, 225.000 patients are treated in 30 clinics, 27 institutes and specialized centers. The over 8.000 employees offer medical care with state-of-the art diagnostics and therapies, which meet highest international standards. Patient care relates to basic and translational research at an internationally competitive level.

We are strong in research and teaching, live diversity, promote potential and are committed to upholding educational equality.

The University Hospital-Essen offers within the

DFG-funded Clinical Research Unit PhenoTImE (CRU 337-2)

3 PhD positions (f/m/d)

Pay grade: 13 TV-L / 65% - temporary employment)

Starting September 1, 2022


The CRU 337 PhenoTImE at the University Hospital Essen and University Duisburg-Essen is based on a unique consortium of internationally renowned basic and clinician scientists with a shared research focus in innovative cancer therapies and tumor-immune crosstalk. Our overall goal is to comprehensively study the molecular mechanisms controlling phenotypic plasticity and immune escape in a distinct assembly of cancers (melanoma, pancreatic ductal adenocarcinoma, glioblastoma) and to reciprocally test our findings across the different cancer entities.

We offer outstanding scientific training and research opportunities for graduates of life sciences with interest in basic and translational cancer research. The exciting research projects comprise epigenetic and metabolic processes inside tumor cells, the reciprocal interaction with microenvironmental parameters, with a focus on the immune system, and the respective effects on tumor cell identities and immune escape. The results will be integrated in comprehensive bioinformatic analyses of genetically and transcriptionally profiled samples as well as publicly available datasets, always in a clinicopathological context.

The promising candidates will be part of a dedicated interdisciplinary team that aims to open new treatment avenues and strategies to prevent drug resistance in cancer.

The following institutes, involved in the CRU, are searching:

  • Division of Translational Skin Cancer Research, German Cancer Consortium (DKTK), University of Duisburg-Essen
  • Division of Translational Neurooncology, West German Cancer Centre, German Cancer Consortium (DKTK), University Hospital Essen
  • Department of Medical Oncology, Laboratory of Molecular Tumorpathology, West German Cancer Center, University Hospital Essen

Requirements:

  • Completed Diploma or Master degree in natural sciences in the field of either Medical Sciences, Cell Biology, Molecular Biology, Immunology, Biochemistry, Biophysics, Bioinformatics, or equivalent disciplines
  • Initial experience with bioinformatics analysis of high throughput analyses
  • First experience in molecular and cell biology techniques and interest in working with patient-derived as well as in vivo model systems
  • Experience with cell culture methods
  • Initial experience with animal experimentation
  • Candidates should be fluent in spoken and written English; knowledge of German is not a requirement.
  • Candidates should have very good computer skills
  • You are flexible, committed and a team player
  • You work independently on your own responsibility and reliably
  • High motivation and commitment for active participation in the interdisciplinary program of the CRU

The University Hospital Essen is an equal opportunity employer. Female scientists are particularly encouraged to apply. The participation in secondary employment depends on the "Hochschulnebentätigkeitsverordnung" of North-Rhine Westphalia. Disabled applicants will be preferentially considered in case of equivalent qualification.

Application

Please send your application documents within 4 weeks after publication of this advertisement on our homepage with reference to the job advertisement number 1250.

Preferably by e-mail in one single PDF file to: bewerbung@uk-essen.de

or in writing to:
University Hospital Essen,
Human Resources Department,
Hufelandstraße 55,
45147 Essen.

We use your data exclusively for application purposes in accordance with the applicable data protection regulations. Further information can be found in the privacy statement on our homepage at: www.uk-essen.de


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