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DFG-funded Clinical Research Unit 337

DFG-funded Clinical Research Unit 337 (CRU 337)

6 PhD position (f/m) E 13 TV-L, 65%
1 PhD position (bioinformatician f/m) – E 13 TV-L, 100%

We are one of the youngest universities in Germany and think in terms of possibilities, not limitations. In the heart of the Ruhrregion, we develop ideas of the future at our 11 faculties. We are strong in research and teaching, live diversity, support potential and are highly committed to an educational equality that has earned this name.

The University Hospital Essen offers first class medical services in the Ruhr metropolis. Every year, 225.000 patients are treated in 26 clinics, 23 institutes and specialized centers. The over 6.000 employees offer medical care with state-of-the art diagnostics and therapies, which meet highest international standards. Patient care is connected with basic and translational research at an international competitive level.

The University Hospital-Essen offers within the

DFG-funded Clinical Research Unit 337 (CRU 337)

6 PhD position (f/m) – E 13 TV-L, 65%

1 PhD position (bioinformatician f/m) – E 13 TV-L, 100%

Starting May 1st, 2019

The CRU 337 PhenoTImE at the Essen University Hospital is based on a unique consortium of internationally renowned basic and clinician scientists with a shared research focus in innovative cancer therapies and tumor-immune cross-talk. Our overall goal is to comprehensively study the molecular mechanisms controlling phenotypic plasticity and immune escape in a distinct assembly of cancers (melanoma, pancreatic ductal adenocarcinoma, glioblastoma, and pilocytic astrocytoma) and to reciprocally test our findings across the different cancer entities.

We offer outstanding scientific training and research opportunities for graduates of life sciences with interest in basic and translational cancer research. The exciting research projects comprise epigenetic processes inside tumor cells, the reciprocal interaction with microenvironmental parameters, first of all the immune system, and the respective effects on tumor cell identities and immune escape. The results will be integrated in comprehensive bioinformatic analyses of genetically and transcriptionally profiled samples as well as publicly available datasets, always in a clinicopathological context.

The promising candidates will be part of a dedicated interdisciplinary team that aims to open new treatment avenues and strategies to prevent drug resistance in cancer.

The following institutes are involved in the CRU:

  • Department of Dermatology, University Hospital Essen
  • Division of Translational Skin Cancer Research, German Cancer Consortium (DKTK), University of Duisburg Essen
  • Division of Translational Neurooncology, West German Cancer Centre, German Cancer Consortium (DKTK), University Hospital Essen
  • Division of Solid Tumor Translational Oncology , West German Cancer Centre, German Cancer Consortium (DKTK), University Hospital Essen
  • Institute of Experimental Immunology and Imaging, University of Duisburg Essen
  • Department of Pediatric Oncology, Hematology, and Clinical Immunology, German Cancer Consortium (DKTK), University Hospital Düsseldorf

We are looking for enthusiastic candidates with a strong Master’s degree (or equivalent) in the field of: Medical Sciences, Cell Biology, Molecular Biology, Immunology, Biochemistry, Biophysics, Bioinformatics, or equivalent disciplines. Candidates should be able to work independently and have a strong interest in the above-mentioned research fields as well as high motivation and commitment for active participation in the interdisciplinary program of the CRU. Candidates are selected on the basis of excellent performance in their studies and their motivation. Candidates should be fluent in spoken and written English; knowledge of German is not a requirement.

Details about the different projects offering positions within the Clinical Research Unit PhenoTImE and extended job descriptions/requirements can be found here.

The positions will be available in May 2019 for up to three years. The salary is in accordance with the German public service salary scale. The pay grade classification depends on the personal and legal requirements.

We are looking forward to your application (incl. cover letter, CV, Bachelor’s, Master’s, references, list of publications, if available). As an option, applicants for PhD student positions can indicate up to three project preferences or if they would like to be considered for any of the available positions. The application deadline is 03/03/2019. Please send your application preferably via email in one single PDF file with reference to the tender number 703 to:

Dr. Juliane Weski
Scientific Coordination Clinical Research Unit 337
Universität Duisburg-Essen
Institute of Experimental Immunology and Imaging
Universitätsstraße 2
45141 Essen
[email protected]

DFG-funded Clinical Research Unit 337

The University Duisburg-Essen aims at promoting the diversity of its members (see here). Applications from disabled or equivalents according to § 2 Abs. 3 SGB IX are encouraged. The participation in secondary employment depends on the “Hochschulnebentätigkeitsverordnung” of North-Rhine Westphalia. The University Duisburg-Essen aims at increasing the share of women in the scientific personnel and therefore explicitly encourages women to apply. Women will be preferentially considered when equally qualified according to the state equality law.

We use your data exclusively for application purposes in accordance with the applicable data protection regulations.

Further information can be found in the privacy statement on our homepage.


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