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EPSRC Centre for Doctoral Training in BioDesign Engineering

EPSRC Centre for Doctoral Training in BioDesign Engineering

The EPSRC Centre for Doctoral Training in BioDesign Engineering aims to train the next generation of leaders at the interface of biology, engineering and data science. The CDT will have an integrative training programme that covers experimentation, automation, coding, data science and entrepreneurship applied to the design, realisation and optimisation of novel biological systems for diverse applications.

The CDT is being led by Imperial College with the University of Manchester and University College London as partners.

All students will undertake the MRes in Systems and Synthetic Biology at Imperial College in their first year, with an extended project at the lead-supervisor institution, followed by a 3 year PhD registration in that host institution.

Our aim is to build an inclusive cohort of students with diverse skillsets from life sciences, engineering and physical/computational backgrounds. We therefore encourage applications from students that reflect this diversity. Applications are open to students with Home fees status as well as those with EU/International fees status. A studentship covers tuition fees as well as a stipend at the UKRI rate for the full duration of the 1+3 programme.

EPSRC Centre for Doctoral Training in BioDesign Engineering

The CDT in BioDesign Engineering is currently inviting applications for the below projects for the 2021 intake. The closing date is Sunday 17th January:

Establishing a synthetic biology toolbox for biosensor development in important probiotic host organisms.

  • Lead supervisor: Prof. Geoff Baldwin (Imperial College London)
  • Co-supervisor: Dr Karen Polizzi (Imperial College London)

Engineering biological complexity in yeast: synthetic pattern formation and emergence

  • Lead supervisor: Dr Naomi Nakayama (Imperial College London)
  • Co-supervisor: Prof. Tom Ellis (Imperial College London)

icRNA: in vivo circular RNAs for efficient expression and control of genes and polyproteins

  • Lead supervisor: Prof. Guy-Bart Stan (Imperial College London)
  • Co-supervisor: Dr Tom Ouldridge (Imperial College London)
  • Co-supervisor: Dr Rodrigo Ledesma-Amaro (Imperial College London)

Microfluidic platforms for the engineering of continuously-operating, synthetic nucleic acid-based systems

  • Lead supervisor: Dr Tom Ouldridge (Imperial College London)
  • Co-supervisor: Dr Claire Stanley (Imperial College London)
  • Co-supervisor: Prof. Guy-Bart Stan (Imperial College London)

Engineering synthetic C1 utilisation in non-conventional organisms for sustainable bioproduction

  • Lead supervisor: Dr Rodrigo Ledesma-Amaro (Imperial College London)
  • Co-supervisor: Dr Patrik Jones (Imperial College London)

Tumor-Targeted Delivery of Synthetic DNA Payloads By Engineered Bacteria

  • Lead supervisor: Prof. Tom Ellis (Imperial College London)
  • Co-supervisor: Dr Teresa Thurston (Imperial College London)
  • Co-supervisor: Prof. Ramesh Wigneshweraraj (Imperial College London)

Design considerations for improved pDNA and therapeutics production

  • Lead supervisor: Dr Francesca Ceroni (Imperial College London)
  • Co-supervisor: Prof. Tom Ellis (Imperial College London)

Optimised construct design for in vitro and in vivo therapeutic production

  • Lead supervisor: Dr Francesca Ceroni (Imperial College London)
  • Co-supervisor: Dr Cleo Kontoravdi (Imperial College London)

Optogenetics for integrated, continuous processes for large-scale chemicals manufacture: Next generation manufacturing through synthetic biology

  • Lead supervisor: Prof. Nigel Scrutton (University of Manchester)
  • Co-supervisor: Dr Sam Hay (University of Manchester)
  • Co-supervisor: Prof. Eriko Takano (University of Manchester)

Engineered genetic bioaugmentation vectors and pathways for bioremediation

  • Lead supervisor: Dr Neil Dixon (University of Manchester)
  • Co-supervisor: Prof. Michael Brockhurst (University of Manchester)

Designing and Engineering Gamma-Butyrolactone Signalling for Synthetic Biology

  • Lead supervisor: Prof. Eriko Takano (University of Manchester)
  • Co-supervisor: Prof. Rainer Breitling (University of Manchester)

Engineering a shape-changing light-actuated living tissue

  • Lead supervisor: Prof. Guillaume Charras (University College London)
  • Co-supervisor: Dr Andela Saric (University College London)

Stochasticity-resilient control of microbial communities in bioprocessing

  • Lead supervisor: Dr Duygu Dikicioglu (University College London)
  • Co-supervisor: Prof. Gary Lye (University College London)