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Newcastle-Liverpool-Durham Doctoral Training Partnership in Biosciences

Newcastle-Liverpool-Durham Doctoral Training Partnership in Biosciences

The Newcastle-Liverpool-Durham DTP is a strategic Partnership in Biosciences doctoral training between three research-intensive universities in northern cities of great industrial heritage, Newcastle University, the University of Liverpool and Durham University.

The Partnership is offering up to 28 four-year BBSRC-funded studentships starting in October 2019. A wide range of projects across the Partnership are available for application under the broad themes of Agriculture & Food Security, Bioscience for Health and World Class Bioscience:

Durham

Analysis of a novel polar auxin transport pathway component in ArabidopsisDetails
Circadian regulation of plant immunity calcium signallingDetails
Copper economy of denitrification by soil microbesDetails
Exploring multi-herbicide resistance in black grassDetails
Identification of genetic effectors that control stem strength in arable crops using a comparative network approachDetails
Identifying and exploiting post-translational modifications in antigen presentation using next generation proteomicsDetails
Protein engineering to enhance the commercial potential of novel fusion protein based biopesticidesDetails
Stem cell derived signals in epithelial homeostasis and ageingDetails
The agri-diagnostic characterisation of algal cell walls for food and biotechnology useDetails
Uncovering new signalling nodes in the interaction between wheat and the fungal pathogen Mycosphaerella graminicolaDetails
Using biochemical and evolutionary approaches to characterise novel enzymes as possible drug targets in apicomplexan parasites of economically important livestockDetails

Liverpool

Identifying nutrient and pesticide modulation of ion channels with Artificial Intelligence (AI)Details
Post-transcriptional gene regulation during chondrogenesisDetails
Cryptosporidium parvum – B-cells as a route to controlDetails
Early development of the avian mucosal immune systemDetails
Identification of drug resistance genes in Fasciola hepatica using a combined in vitro phenotyping and pooled genotyping approachDetails
Novel approaches for defining the Gram negative mobile antimicrobial resistance reservoir in poultry farming environments under varying antimicrobial selective pressureDetails
Patterns of antimicrobial use and resistance in a cohort of UK dairy farmsDetails
Phage WO as a vehicle to transform Wolbachia, a symbiont of major crop pestsDetails
Understanding patterns of AMR selection and transmission between sheep and their environmentDetails
Adhesion force regulation as a mechanism of cell adaptation to tissue stiffness and composition in health and diseaseDetails
Are farm animal-associated Salmonella hyper-susceptible to bacteriophage killing?Details
Bioengineering of bacterial CO2-concentrating system for improved photosynthesisDetails
Characterising genetic diversity of Wild Rocket (Diplotaxis tenuifolia (L.) DC) and developing a pipeline for marker assisted breedingDetails
Effect of transposable element insertions on gene expressionDetails
Engineering a water retention system for plants based on novel polysaccharide sulfotransferases from red algaeDetails
Engineering more water-use efficient crops: functional genomics of the circadian control of CO2 fixation associated with Crassulacean acid metabolismDetails
Improving photosynthetic efficiency - engineering and evolution of light-harvesting complexesDetails
Integrating antimicrobial resistance mechanisms of Staphylococcus aureusDetails
Non-canonical signalling mechanisms in phagosome maturationDetails
Optimising reproductive organ photosynthesis to improve seed oil contentDetails
Understanding the biology of TEX12 as a centrosomal proteinDetails
Using machine learning to identify the functional consequences of naturally occurring variants in the rice genomeDetails
Using stem cell-derived “mini-guts” to determine the role of the microbiota in resistance to Cryptosporidium infection in cattleDetails
Aetiopathogenesis and genomic architecture of resistance to claw horn disruption lesions in dairy cattleDetails
Preventing neonatal infectious arthritis in lambs: sources, transmission and characterisation of Streptococcus dysgalactiaeDetails

Newcastle

Cyanobacterial synthetic biology tools derived from bacteriophagesDetails
Epigenetic control of transcription termination in plant developmentDetails
Exploring the importance of fungal-specific aspects of RNase MRP in ribosome productionDetails
How do cells generate functional asymmetries?Details
Mechanisms of interbacterial competition during Staphylococcus aureus colonisationDetails
Novel RNA polymerases, and insights into molecular biology of agricultural, biotechnological and pathogenic bacteria containing themDetails
Optimising protein production from high density Bacillus subtilis cultures by suppressing autolysisDetails
Plant fibre degradation by the human and animal gut microbiotaDetails
Regulation of ribosome modification as a means to enhance anti-fungal antibiotic efficacyDetails
Targeting stress activated MAPK pathways in eukaryotic pathogensDetails
The importance of metal binding for the function of rice proteins that interact with pathogen effectorsDetails
The molecular structure and function of the synaptonemal complex in chromosome synapsis and recombination during meiosisDetails
The role of iron storage ferritins in the supply of iron to metalloproteinsDetails
The role of two component signalling in the regulation of stress responses and virulence in the fungal phytopathogen, Zymoseptoria triticiDetails
Understanding Salmonella-Plant Interactions and Signalling: Implications in Fresh Produce Safety and ControlDetails
Urease metabolism in the wheat pathogen Zymoseptoria triticiDetails
Building a microbial endophyte chassis for enhanced plant productivityDetails
Designing better Rubisco for crops: Predicting effects of amino acid substitutions on Rubisco kinetics using machine learningDetails
Integration of metabolic and developmental cues by the Arabidopsis endospermDetails
Interactions between housing environment, chronic stress, and pathogenic infections in laying hensDetails
The role of Vitamin D in enhancing the different arms of the immune response in broiler chickensDetails
Understanding the structure and function of a new bacterial iron storeDetails

BBSRC DTP CASE awards enable students to undertake research projects that involve both an academic and non-academic partner. CASE studentships provide outstanding students with access to training, facilities and expertise not available in an academic setting. The partner organisation also benefits from recruiting a motivated, doctoral student who is capable of undertaking cutting-edge research.

All studentships will cover a tax-free stipend at the UK Research and Innovation rate (indicative amount in year 1 in 2018/19 is £14,777, research costs and tuition fees, and are available to UK students and to EU citizens who have been in the UK for the three years prior to the academic year 2018-19. Fees only studentships (no stipend) are available to EU citizens who have been a resident of the EU but not UK.

Further information about eligibility for UK Research and Innovation funding can be found at the following website.

Students who have, or are expecting to attain, at least an upper second class honours degree (or equivalent) in a relevant subject, are invited to apply by completing the online application form and attaching a full CV and covering letter by 11 January 2019. Informal enquires may be made by email to the relevant supervisor.

The multidisciplinary training experience and interdisciplinary nature of some of the projects means that we welcome applications from students with physical science and mathematical backgrounds who are interested in using their skills to address the challenges of 21st century bioscience research.

Doctoral Training Partnership in Biosciences

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