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PhD fellowship in the Hoffmann Group at the Center for Chromosome Stability (CCS)

PhD fellowship in the Hoffmann Group at the Center for Chromosome Stability (CCS)

Department of Cellular and Molecular Medicine, University of Copenhagen & Human Genetics Unit at the University of Edinburgh

A PhD position is available in the Center for Chromosome Stability, University of Copenhagen, Denmark, and the Human Genetics Unit at the University of Edinburgh, United Kingdom. The position is available from 1 August 2022 (or at a mutually agreed date). Highly motivated and committed candidates with experience and interest molecular aging and chromosome instability in human eggs are invited to apply.

The position is fully funded, although the post-holder will be encouraged to seek a personal fellowship to support their PhD stipend. The first 12 months will be spent in Prof. Ian Adams lab at the Human Genetics Unit and the subsequent 24 months at the University of Copenhagen in the lab of Prof. Eva Hoffmann.

Your registration as a PhD fellow will be at the Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

Project description

The project aims at understanding the molecular mechanisms that result in the high incidence of chromosomal errors (aneuploidy) in human eggs. This project will involve cytological and genomic analyses of human eggs as well as relevant model systems such as mouse and in vitro generated oocytes. Metabolic influences on the process will also be elucidated, including wet lab experimentation and data analysis of aneuploidy incidence associated with polycystic ovarian syndrome.

The research will benefit from access to unique clinical material and methodologies at both sites. The project will be overseen by Profs Ian Adams (Edinburgh) and Eva R Hoffmann (Copenhagen). The successful candidate will be expected to participate in a broad range of scientific activities related to their research as well as PhD courses and educational activities.

Place of employment

The place of employment is at the Department of Cellular and Molecular Medicine (ICMM), University of Copenhagen. Our lab at the ICMM offers a creative and ambitious scientific environment, with nine different nationalities presently represented and English as the working language. We strive to produce research results with high international impact, focusing on the functional cell, its genetic components, and molecular cellular mechanisms in a medical context.

The ICMM currently comprises five research programs, three high profile Research Centers as well as a number of internationally renowned research groups. The scientists at ICMM are involved in high quality research based undergraduate and graduate teaching programs at the University of Copenhagen.

More details can be found at: https://icmm.ku.dk/english/.

Application Process

Your application must be submitted electronically by clicking "Apply now". The application must include the following documents in PDF format:

  1. Motivated letter of application (max. one page).
  2. CV incl. education, experience, language skills and other skills relevant for the position.
  3. A certified/signed copy of Master of Science certificate. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor will do.
  4. For applicants from non-English speaking countries, a test result of internationally recognized English test, e.g., IELTS, or TOEFL.
  5. Publication list (if possible)

Application deadline: Sunday 24 April, 2022, 23.59 p.m. CET.

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

Questions

General information about PhD programs at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/

Specific questions related to CCS and the procedures for registering as a PhD fellow should be addressed to Elin Ølgaard by e-mail: ee@sund.ku.dk

Questions concerning project details can be addressed to Professor Eva Hoffmann by e-mail: eva@sund.ku.dk