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PhD studentship opportunities in Environment and Health based at the National Heart and Lung Institute

PhD studentship opportunities in Environment and Health based at the National Heart and Lung Institute

We are pleased to invite applications for a 3-year PhD studentship in the MRC Centre for Environment and Health based at the National Heart and Lung Institute.

This studentship will explore the burden, cause and prognosis of relevant non-communicable cardio-respiratory diseases with a particular focus on the role of the environment (indoor, outdoor, occupational).

Candidates should have experience in at least one of the following areas:

  • Epidemiology
  • Biostatistics including statistical genetics
  • Environmental exposure assessment
  • Molecular signatures of exposures and disease pathways

We wish to train and develop the next generation of epidemiologists in primary data collection and/or analysis of health and exposure information in large scale population and occupational surveys. Students will have access to state-of-the art facilities, supported by a bespoke training programme.

Example projects are below but we will consider candidates with interest in other areas of our work (contact Professor Deborah Jarvis d.jarvis@imperial.ac.uk to discuss):

Occupational epidemiology: This project will identify molecular markers of injury and their long-term outcomes using information from a prospective cohort study of UK servicemen severely injured in the Afghan conflict. Work includes identification of associations in injured cases and controls using metabolomic and proteomic profiles, including development of machine learning approaches (Supervisors - Professor Paul Cullinan/ Professor Marc Dumas/ Dr Johanna Feary).

Indoor environment and respiratory health: This project will examine the role of indoor exposures on the onset and exacerbation of asthma COPD, as well as other adult respiratory and allergic health outcomes. Work includes examining high-risk subgroups, genetic susceptibility, and the effect of combined exposures or interactions between indoor and outdoor factors, using data from available cohorts with opportunities for new data collection. (Supervisors Professor Deborah Jarvis/Dr Elaine Fuertes).

Occupational lung disease in low- and middle-income countries (LMICs): This project will examine the role of workplace exposures in chronic lung diseases using the Burden of Obstructive Lung Disease (BOLD) study. BOLD has high-quality post-bronchodilator lung function and occupational data from adults in several LMICs. To close an important gap in occupational epidemiology, the student will also develop a new tool suitable for collection of lifetime job histories in LMICs (Supervisors - Dr Andre Amaral/Prof Paul Cullinan).

Respiratory health and the environment in low- and middle-income countries (LMICs): This project will examine the relationship between respiratory health and environmental factors (e.g., household air pollution from biomass use; outdoor air pollution; vegetation index; pesticide use) in LMICs using baseline and follow-up data from the BOLD study. BOLD has collected high-quality data on lung function and risk factors from about 30,000 people from 41 sites, mostly in LMICs. There will be opportunities for new data collection (Supervisors - Professor Deborah Jarvis/Dr Andre Amaral).

PhD studentship opportunities in Environment and Health based at the National Heart and Lung Institute

For more information, and instructions on how to apply, visit environment-health.ac.uk/phd-studentships/.

The MRC Centre is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment.

The closing date for applications is 31st May 2021, and studentships are expected to start no later than 1st October 2021.