About the Project
The student appointed to this project will used cutting edge microfluidics to formulate nanoparticles (liposomes, polymer based) encompassing poorly soluble drugs against each energy pathway. The project will be comprised of two main arms: i) a pharmaceutics arms investigating nanoparticle composition, drug loading, drug release, stability etc. and ii) a cell biology arm where the nanoparticles will be tested for anti-tumour efficacy alone or in combination with chemo- and/or radiotherapy. These experiments will also be conducted under variable oxygen concentrations to establish efficacy against treatment resistant hypoxic cells.
This projects forms part of an exciting collaborative partnership between Dr Jonathan Coulter, a prostate cancer expert in translational medicine and Dr Dimitrious Lamprou, a Reader in pharmaceutical engineering with expertise in microfluidics and controlled release systems.
Important, applicants must fulfil the eligibility criteria set out by the Department for the Economy which can be found at this link: View Website
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