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A Multimodal Complex Flow Phantom for Diagnostic Imaging


Project Description

This PhD concerns development and evaluation of a multimodal, MRI-compatible complex flow phantom for diagnostic imaging, designed to generate reproducible complex flows, with well characterized pulsatility, acceleration and vorticity.

Proposal:
The project will design and construct a novel, prototype, complex flow rig (compatible with MRI, CT, ultrasound (U/S)) that overcomes the limitations of current flow phantoms. Flow field complexity and reproducibility of this novel multimodal phantom will be characterized with computational fluid dynamics (CFD) and experimental flow visualization, establishing flow behaviour within known tolerances. The performance of the rig as a complex flow phantom will be evaluated with clinical MRI, U/S and CT flow imaging technologies, and its utility will be compared with currently accepted standards. The technology is expected to reveal inadequacies of current diagnostic techniques, leading to specification for a commercially exploitable phantom.

This is a demanding project that combines mathematics, physics/engineering, computational simulation and experimental design/measurement to improve diagnostic measurement in the clinic.  It will be supported by a diverse training programme and an enthusiastic collaborative supervisory team, including expertise from industry and the NHS. The work will build on a track record in ultrasound ring vortex phantom design (see The Ring Vortex: a candidate for a liquid-based complex flow phantom for medical imaging. Ferrari S, Ambrogio S, Walker A, Narracott A, Fenner J. Lecture Notes in Computational Vision and Biomechanics 2017 27:893-902), involving Medical Physics (University of Sheffield), Leeds Test Objects Ltd. (LTO - http://www.leedstestobjects.com) and Sheffield Teaching Hospitals NHS Foundation Trust.

Enquiries:
Interested candidates should in the first instance contact Dr John Fenner ()

How to Apply:
Please complete a University Postgraduate Research Application form available here: http://www.shef.ac.uk/postgraduate/research/apply

Please clearly state the prospective main supervisor in the respective box and select Department of Infection, Immunity and Cardiovascular Disease as the department.

Interviews are due to take place on Monday 25th March 2019.

Funding Notes

The Faculty of Medicine, Dentistry and Health has received an allocation of three EPSRC studentships for 2019 entry from the Doctoral Training Partnership grant that is awarded to the University of Sheffield to fund PhD studentships in the EPSRC remit. These studentships will be 42 months in duration, and include home fee, stipend at RCUK rates and a research training support grant (RTSG) of £4,500.

Home/EU students must have spent the 3 years immediately preceding the start of their course in the UK to receive the full funding.

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