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A Nutrigenetics approach to study gene-diet interactions on Obesity in a Brazilian population


Project Description

We are seeking a highly motivated candidate for a PhD project that will focus on genetic epidemiology and statistical genetics. The project will focus on identifying genetic determinants of obesity and investigating the effect of these genetic determinants and dietary factors on obesity traits in a Brazilian population using detailed epidemiological and functional analyses.

The student will spend 1 year in Brazil to conduct a population-based study and do sample collection and will spend the remaining 2 years at the University of Reading, UK, to perform genetic association and gene-diet interaction (nutrigenetics) analyses using appropriate statistical softwares. Specific emphasis will be placed on the development of novel analytical approaches to the analysis of hypotheses related to gene-diet interactions. The student will receive training in genetic epidemiology, statistical genetics and bioinformatics. The student will also have the opportunity to discuss the exact title and nature of the project to suit their interests and to incorporate recent advances in these exciting areas.

This project provides an opportunity to work with a group that has a strong track record in nutritional and genetic epidemiology and to develop links with experts nationally and internationally. The successful candidate will be expected to actively participate in group meetings such as journal clubs and department seminars.

The project will be carried out at the Hugh Sinclair Unit of Human Nutrition, University of Reading, UK. The project will be supervised by Dr Vimal Karani, Programme Leader in Genetic and Nutritional Epidemiology.
For an informal discussion, contact Dr Vimal Karani ().

Funding Notes

BSc (grade 2:1 or 1) or MSc (merit or distinction) in a relevant subject

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