Analysis of Magnetically Susceptible Nanoparticles via confocal and fluorescence spectroscopy

A project is requested for a student to design a device capable of studying medically targeted nanoparticles (with potential applications in cancer therapy) under both microscopic and fluorescence devices. This will work by altering the magnetic field of nanoparticles to allow induction heating within a confocal microscope environment, allowing biomedical scientists to observe the direct action of these novel materials at the biological interface.

Once the device is prepared the student will examine the behaviour of the nanoparticles to gain better understanding of their solution properties and interactions with macromolecular materials. The student will additionally study time dependent fluorescence activities of these nanoparticles during the magnetic heating process, gaining a more thorough understanding of their solution behaviour and biological activities.

Training will be offered on imaging techniques (i.e. TEM, SEM, confocal, spectroscopy) and materials synthesis (ie. Polymers, nanoparticles) to facilitate advanced studies. Expertise in scientific analytical equipment (both usage and maintenance) is required.