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Application of a novel particle coating technology for paediatric formulation development

  • Full or part time
  • Application Deadline
    Thursday, April 30, 2020
  • Funded PhD Project (European/UK Students Only)
    Funded PhD Project (European/UK Students Only)

Project Description

Applications are invited for a three year Postgraduate studentship to be undertaken within the School of Life and Health Sciences at Aston University. The successful applicant will join an established experimental group working with Prof Afzal Mohammed and Dr Affiong Iyire.

Background to the Project

Dry particle coating developed at Aston is a novel particle engineering technology that, for the first time, will permit layering of fine particles over coarse particles through fluidisation and meticulous precision control of processing parameters. This project will involve understanding the impact of processing parameters during dry coating on the stability and performance of small drug molecules and biologics such as peptides and proteins. Following the optimisation of formulations, work in this project will involve cell culture based transport and toxicity studies to develop a mechanistic understanding of formulation performance in vivo. Additionally, characterisation studies including HPLC, protein/peptide stability indicating assays, laser diffraction studies to study particle size and charge will be carried out to characterise powder blends.

Person Specification

The successful applicant should have been awarded, or expect to achieve, a Masters degree with a 60% or higher weighted average, and/or a First or Upper Second Class Honours degree (or an equivalent qualification from an overseas institution), in a biological science or a related subject.

Contact information

For formal enquiries about this project contact Prof Afzal Mohammed by e-mail:

Submitting an application

Details of how to submit your application, and the necessary supporting documents can be found here. Please ensure to quote “Particle Coating_Afzal” on your application.

Please note that a project proposal is not required, however your personal statement should address your ability & knowledge of the research area.

If you require further information about the application process please contact the Postgraduate Admissions team at

Funding Notes

This studentship includes a fee bursary to cover the home/EU fees rate, plus a maintenance allowance of £15,009 in 2019/20 (subject to eligibility).

[[Overseas Applicants]]
This studentship includes a fee bursary to cover the home/EU fees rate plus a maintenance allowance of £15,009 in 2019/20.

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