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Application of animal corneal cells for skin regeneration, tissue engineering and wound healing enhancement


   Faculty of Life Sciences


About the Project

Engineering of biological skin substitutes has progressed over the years from individual applications of skin cells, or biopolymer scaffolds, to combinations of cells and scaffolds for treatment, healing, and closure of acute and chronic skin wounds. There are three groups in this area: acellular scaffolds, temporary substitutes containing allogeneic skin cells, and permanent substitutes containing autologous skin cells. The combined use of acellular dermal substitutes with permanent skin substitutes containing autologous cells has been shown to effectively cure even extensive burns involving more significant than 90% of the total body surface area (Boyce and Lalley, 2018). The cornea has a unique avascular structure. Therefore, the translational potential in the cornea to repair damaged cells in the wound will be investigated.

The design of this project can not be published due to highly confidentiality of the project. Also, this project was introduced and involved in the Research and Knowledge Transfer Support (RKTS)

The suitable PhD student should be an enthusiastic researcher with punctuality, creativity, hard worker and well-organized plan in the project. The requirement for this project would be excellent communication skills with the MSc in a relevant subject.

This project aims to investigate the mechanism of action and also, the feasibility of the use of animal cornea in wound healing.

Funding Notes

This is a self-funded PhD project; applicants will be expected to pay their own fees or have a suitable source of third-party funding. A bench fee may also apply to this project, in addition to the tuition fees. UK students may be able to apply for a Doctoral Loan from Student Finance for financial support.

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