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Approaches for the design of prostate proteomic projects and their analysis integrated with other molecular data

   School of Mathematics and Statistics

   Applications accepted all year round  Competition Funded PhD Project (Students Worldwide)

About the Project

The CRUK-funded International Cancer Genome Consortium prostate has generated whole-genome sequencing data, DNA-methylation sequencing data, mRNA expression data and small RNA data for a cohort of prostate cancer patients. For a subset of these patients protein samples have been banked, and some data have been generated in two ‘pilot’ mass-spectrometry experiments. While standard analysis methods could be applied, the design of our experiments invites the development of new methods, especially when one considers the additional molecular and clinical data we have available to us.

This project will look to perform an analysis of those proteomics data, developing methods as appropriate. It may also move into considering which additional data should be generated and designing a further experiment.

For more information, including how to apply, please see this document (pdf file): Postgraduate Opportunities in Statistics. See also the School’s Postgraduate Research web page.

Funding Notes

Full funding (fees, plus stipend of approx. £17,668) is available for well-qualified students; we encourage applications as soon as possible to maximize your chances of being funded. UK, EU and other overseas students are all encouraged to apply. New PhD students would typically start in September 2023, but this is flexible.
More information is available School's Postgraduate Research web page - please see the link under "About this project".

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