Assessment of nanomaterial toxicity using alternative, non-rodent models
The PhD will employ complex 3D in vitro or zebrafish embryo models to assess the toxicity of nanomaterials of varied physico-chemical properties to investigate impacts on the lung, immune system or intestine.
Nanomaterials (NMs) are used across different sectors (e.g. cosmetics, nanomedicines, electronics, food), and human exposure to nanomaterials is increasing in occupational, environmental and consumer settings. Despite the increased prevalence of NMs in the marketplace, there are still uncertainties surrounding their potential impact on humans and the environment and therefore it is important to assess their toxicity so that nanotechnology can develop in a safe, sustainable and responsible way. When assessing the toxicity of nanomaterials it is essential to encourage the use of alternatives to rodent testing for ethical, financial, legislative and time considerations. Accordingly, this PhD will employ complex 3D in vitro or zebrafish embryo models to assess the toxicity of nanomaterials of varied physico-chemical properties to investigate impacts on the lung, immune system or intestine.
Applicants should have a degree in a relevant area (e.g. Biomedical sciences, Biological Sciences, Toxicology, Pharmacology, Cell and Molecular Biology). Only students from the UK or EU are eligible to apply.
Requirements All applicants must have or expect to have a 1st class MChem, MPhys, MSci, MEng or equivalent degree by Autumn 2019. Selection will be based on academic excellence and research potential, and all short-listed applicants will be interviewed (in person or by Skype). DTP’s are only open to UK/EU applicants.
Level of Award The annual stipend will be £15k and full fees will be paid for 3 years.
Closing Date All applications must be received by 8th February 2019. All successful candidates must commence studies by 1st December 2019 at the very latest.
How to Apply When applying through the Heriot-Watt on-line system please ensure you provide the following information:
(a) in ‘Study Option’
You will need to select ‘Edinburgh’ and ‘Postgraduate Research’. ‘Programme’ presents you with a drop-down menu. Choose Bio-Engineering & Bio-Science PhD, Chemistry PhD, Physics PhD, Chemical Engineering PhD, Mechanical Engineering PhD or Electrical PhD as appropriate and select October 2018 for study option (this can be updated at a later date if required)
(b) in ‘Research Project Information’
You will be provided with a free text box for details of your research project. Enter Title and Reference number of the project for which you are applying and also enter the supervisor’s name.
This information will greatly assist us in tracking your application.
Please note that once you have submitted your application, it will not be considered until you have uploaded your CV and transcripts.