Number of awards
1
Start date and duration
Preferably 27 September 2021 for 4 years.
Overview
Skin ageing is a complex process that is determined by both intrinsic and extrinsic factors, which leads to a progressive loss of structure and function. Extrinsic skin ageing is driven to a large extent by environmental factors and external stressors such as the components of sunlight, pollution and lifestyle factors have been shown to stimulate the production of reactive oxygen species and generate oxidative stress. The damage from these exogenous sources can impair skin structure and function leading to the phenotypic features of extrinsic skin ageing.
The project will Investigate the cellular pathway changes within skin in response to different combinational components of solar light and sunscreen interventions and will build upon our previously published study (Hudson et al., FASEB 2020 Mar; 34(3): 3874-3883). This project is multi-disciplinary including cellular, molecular biological and physiological techniques, image analysis, cell culture, genetic and chemical analysis, immunostaining and gene expression.
Sponsor
BBSRC and Croda Europe Limited (UK)
Name of supervisor(s)
The supervisory team will be led by Professor Birch-Machin (Newcastle University) and Dr Chavan (Croda expert).
Eligibility Criteria
You must have a minimum of an upper-second class Honours degree or International equivalent in an appropriate biomedical sciences subject area. A further research qualification at Master’s level (for example an MRes in an appropriately related field) is an advantage.
This award is available to UK/International applicants.
To study this course you need to meet the following English Language requirements:
IELTS 6.5 overall (with a minimum of 5.5 in all other sub-skills).
How to apply
You must apply through the University’s online postgraduate application system. To do this please ‘Create a new account’.
Only mandatory fields need to be completed. However, you will need to include the following information:
•insert the programme code 8300F in the programme of study section
•select ‘PhD in the Faculty of Medical Sciences (full time)– Dermatology' as the programme of study
•insert the studentship code TC024 in the studentship/partnership reference field
•attach a covering letter and CV. The covering letter must state the title of the studentship, quote the studentship reference code TC024 and state how your interests and experience relate to the project
•attach degree transcripts and certificates and, if English is not your first language, a copy of your English language qualifications.
Contact
Informal enquiries to lead supervisor: Professor Mark Birch-Machin; [Email Address Removed]. Translational and Clinical Research Institute, Medical school, Faculty of Medical Sciences, Newcastle University.
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